Skip to main content
SpringerLink
Log in

Wondhelingsproblemen in de mond

  • Chapter
  • First Online:
Book cover Het tandheelkundig jaar 2017

  • 358 Accesses

Samenvatting

Een intacte gelaatshuid en een intacte mucosa in de mond zijn belangrijke verdedigingslinies. Wanneer deze doorbroken worden door een wond, een tandextractie of een operatieve ingreep, komt er een helingsproces op gang met een vaste volgorde. Na de bloedstelping volgt een fase van ontsteking, waarbij jong vaatrijk celrijk bindweefsel wordt gevormd. Vervolgens vormt de wond vanuit de randen nieuw slijmvlies, waarna de wond gaat samentrekken en een litteken achterlaat. Zowel plaatselijke als algemene factoren kunnen dit normale proces van wondheling in de mond verstoren en aanleiding geven tot een vertraagde, uitgestelde of onvolledige wondheling. Ook kan te veel littekenvorming plaatsvinden. Oorzaken van verstoorde wondheling die relevant zijn voor de tandheelkundige praktijk worden in dit hoofdstuk besproken.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 89.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Hardcover Book
USD 119.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Literatuur

  • Adell R, Eriksson B, Nylén O, Ridell A. Delayed heating of fractures of the mandibular body. Int J Oral Maxillofac Surg. 1987;16:15–24.

    Article  PubMed  Google Scholar 

  • Broughton G 2nd, Janis JE, Attinger CE. Wound healing: an overview. Plast Reconstr Surg. 2006;117:1eS–32S.

    Google Scholar 

  • Brower MC, Johnson ME. Adverse effects of local anesthetic infiltration on wound healing. Reg Anesth Pain Med. 2003;28(3):233–40.

    Article  PubMed  Google Scholar 

  • Cohen IK, Diegelmann RF, Lindblad WJ. Wound healing: biochemical and clinical aspects. Philadelphia: WB. Saunders Company; 1992:541–61, 630.

    Google Scholar 

  • Dauwe PB, Pulikkottil BJ, Lavery L, Stuzin JM, Rohrich RJ. Does hyperbaric oxygen therapy work in facilitating acute wound healing: a systematic review. Plast Reconstr Surg. 2014;133(2):208e–15e.

    Article  PubMed  Google Scholar 

  • Dietrich EM, Antoniades K. Molecularly targeted drugs for the treatment of cancer: oral complications and pathophysiology. Hippokratia. 2012;16(3):196–9.

    PubMed  PubMed Central  Google Scholar 

  • Discepoli N, Vignoletti F, Laino L, Sanctis M de, Munoz F, Sanz M. Early healing of the alveolar process after tooth extraction: an experimental study in the beagle dog. J Clin Periodontol. 2013;40:638–44.

    Google Scholar 

  • Dodson TB. HIV status and the risk of post-extraction complications. J Dent Res. 1997;76(10):1644–52.

    Article  PubMed  Google Scholar 

  • Dogan N, Uçok C, Korkmaz C, Uçok O, Karasu HA. The effects of articaine hydrochloride on wound healing: an experimental study. J Oral Maxillofac Surg. 2003;61(12):1467–70.

    Article  PubMed  Google Scholar 

  • Dunda SE, Bozkurt A, Pallua N, Krapohl BD. Reconstructive surgery in immunocompromised patients: evaluation and therapy. GMS Interdiscip Plast Reconstr Surg DGPW. 2015;4:Doc18.

    Google Scholar 

  • Glim JE, Egmond M van, Niessen FB, Everts V, Beelen RH. Detrimental dermal wound healing: what can we learn from the oral mucosa? Wound Repair Regen. 2013;21(5):648–60.

    Google Scholar 

  • Goldberg M. The Dental pulp. Biology, pathology, and regenerative therapies. Springer;2014. p. 282.

    Google Scholar 

  • Guo S, Dipietro LA. Factors affecting wound healing. J Dent Res. 2010;89(3):219–29.

    Article  PubMed  PubMed Central  Google Scholar 

  • Hollander JE, Singer AJ. Laceration management. Ann Emerg Med. 1999;34:356–67.

    Article  PubMed  Google Scholar 

  • Hom DB, Hebda PA, Gosain AK, Friedman CD. Essential tissue healing of the face and neck. BC Decker Inc. People’s medical Publishing House: Shelton, Connecticut. 2009. pag. 24–25.

    Google Scholar 

  • Jung MK, Callaci JJ, Lauing KL, Otis JS, Radek KA, Jones MK, Kovacs EJ. Alcohol exposure and mechanisms of tissue injury and repair. Alcohol Clin Exp Res. 2011;35(3):392–9.

    Article  PubMed  Google Scholar 

  • Junqueira LC, Carneiro J. Functionele histologie. 11e druk. Maarssen: Elsevier Gezondheidszorg; 2007. p. 182.

    Google Scholar 

  • Karamanos E, Osgood G, Siddiqui A, Rubinfeld I. Wound healing in plastic surgery: does age matter? An American college of surgeons national surgical quality improvement program study. Plast Reconstr Surg. 2015;135(3):876–81.

    Article  PubMed  Google Scholar 

  • Larjava H. Oral wound healing. Cell biology and clinical management. 1st ed. Hoboken (NJ): Wiley-Blackwell; 2012. p. 1.

    Google Scholar 

  • Larson BJ, Longaker MT, Lorenz HP. Scarless fetal wound healing: a basic science review. Plast Reconstr Surg. 2010;126:1172–80.

    Article  PubMed  PubMed Central  Google Scholar 

  • Lee IJ, Koom WS, Lee CG, Kim YB, Yoo SW, Keum KC, et al. Risk factors and dose-effect relationship for mandibular osteoradionecrosis in oral and oropharyngeal cancer patients. Int J Radiat Oncol Biol Phys. 2009;75(4):1084–91.

    Article  PubMed  Google Scholar 

  • Linde J, Lang NP. Clinical periodontology and implant dentistry. 6th ed. 2 Volumes. Hoboken (NJ): Wiley Blackwell;2015. p. 1372.

    Google Scholar 

  • McDaniel JC, Massey K, Nicolaou A. Fish oil supplementation alters levels of lipid mediators of inflammation in microenvironment of acute human wounds. Wound Repair Regen. 2011;19(2):189–200.

    Article  PubMed  PubMed Central  Google Scholar 

  • Momeni A, Kim RY, Kattan A, Tennefoss J, Lee TH, Lee GK. The effect of preoperative radiotherapy on complication rate after microsurgical head and neck reconstruction. J Plast Reconstr Aesthet Surg. 2011;64(11):1454–9.

    Article  PubMed  Google Scholar 

  • Moraschini V, Barboza ESP. Effect of autologous platelet concentrates for alveolar socket preservation: a systematic review. Int J Oral Maxillofac Surg. 2015;44:632–41.

    Article  PubMed  Google Scholar 

  • Mücke T, Rau A, Weitz J, Ljubic A, Rohleder N, Wolff KD, et al. Influence of irradiation and oncologic surgery on head and neck microsurgical reconstructions. Oral Oncol. 2012;48(4):367–71.

    Article  PubMed  Google Scholar 

  • Nabil S, Samman N. Risk factors for osteoradionecrosis after head and neck radiation: a systematic review. Oral Surg Oral Med Oral Pathol Oral Radiol. 2012;113(1):54–69.

    Article  PubMed  Google Scholar 

  • Nadella KR, Kodali RM, Guttikonda LK, Jonnalagadda A. Osteoradionecrosis of the jaws: clinico-therapeutic management: a literature review and update. J Maxillofac Oral Surg. 2015;14(4):891–901.

    Article  PubMed  Google Scholar 

  • Nas S. Postoperative infection rates in HIV positive patients with mandibular fractures J Oral Maxillofac Surg. 2006;64 (9Suppl.):33.

    Google Scholar 

  • Politis C, Lambrichts I, Agbaje JO. Neuropathic pain after orthognathic surgery. Oral Surg Oral Med Oral Pathol Oral Radiol. 2014;117(2):e102–7.

    Article  PubMed  Google Scholar 

  • Rodriguez-Merchan EC. Surgical wound healing in bleeding disorders. Haemophilia. 2012;18(4):487–90.

    Article  PubMed  Google Scholar 

  • Roy S, Das A, Sen CK. Disorder of localized inflammation in wound healing: a systems perspective. In: Vodovotz T, An G (eds.). Complex systems and computational biology. Approaches to acute Inflammation. New York: Springer Science+Business Media; 2013. p. 173–83.

    Google Scholar 

  • Schmidt B, Kearns G, Perrott D, Kaban LB. Infection following treatment of mandibular fractures in human immunodeficiency virus seropositive patients. J Oral Maxillofac Surg. 1995;53(10):1134–9.

    Article  PubMed  Google Scholar 

  • Schreml S, Szeimies RM, Prantl L, Karrer S, Landthaler M, Babilas P. Oxygen in acute and chronic wound healing. Br J Dermatol. 2010;163:257–68.

    Article  PubMed  Google Scholar 

  • Serhan CN, Petasis NA. Resolvins and protectins in inflammation resolution.Chem Rev. 2011;111(10):5922–43.

    Google Scholar 

  • Shafer WG, Hine MK, Levy BM, Tomich CE. A textbook of oral pathology. 4th ed. Philadelphia: WB Saunders Company; 1983;917:594–6.

    Google Scholar 

  • Simopoulos AP. Evolutionary aspects of diet: The Omega-6/Omega-3 Ratio and the Brain. Mol Neurobiol. 2011;44:203–15.

    Article  PubMed  Google Scholar 

  • Sørensen LT. Wound healing and infection in surgery: the pathophysiological impact of smoking, smoking cessation, and nicotine replacement therapy a systematic review. Ann Surg. 2012;255:1069–79.

    Article  PubMed  Google Scholar 

  • Stoelinga PJW, Brouns JJA, Merkx. MAW. Mondchirurgie voor tandartsen. Houten: Bohn Stafleu van Loghum; 2009. p. 204.

    Google Scholar 

  • Sulaiman F, Huryn JM, Zlotolow IM. Dental extractions in the irradiated head and neck patient: a retrospective analysis of memorial sloan-kettering cancer center protocols, criteria, and end results. J Oral Maxillofac Surg. 2003;61(10):1123–31.

    Article  PubMed  Google Scholar 

  • Trombelli L, Farina R, Marzola A, Bozzi L, Liljenberg B, Lindhe J. Modeling and remodeling of human extraction sockets. J Clin Periodontol. 2008;35:630–9.

    Article  PubMed  Google Scholar 

  • Tsai CJ, Hofstede TM, Sturgis EM, Garden AS, Lindberg ME, Wei Q, et al. Osteoradionecrosis and radiation dose to the mandible in patients with oropharyngeal cancer. Int J Radiat Oncol Biol Phys. 2013;85(2):415–20.

    Article  PubMed  Google Scholar 

  • Wang AS, Armstrong EJ, Armstrong AW. Corticosteroids and wound healing: clinical considerations in the perioperative period. Am J Surg. 2013;206(3):410–7.

    Article  PubMed  Google Scholar 

  • Xie P, Jia S, Tye R, Chavez-Munoz C, Vracar-Grabar M, Hong SJ, et al. Systemic administration of hemoglobin improves ischemic wound healing. J Surg Res. 2015;194(2):696–705.

    Article  PubMed  Google Scholar 

  • Yip WL. Influence of oxygen on wound healing. Int Wound J. 2015;12(6):620–4.

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Faculteit Geneeskunde, Diensthoofd MKA, KU Leuven, UZ Leuven, Belgium

    C. Politis

  2. Departement Beeldvorming en Pathologie & Dienst MKA, KU Leuven, Onderzoeksgroep OMFS-IMPATH, UZ Leuven, Belgium

    C. Politis, J. Agbaje, R. Jacobs & J. Schoenaers

Authors
  1. C. Politis
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. J. Agbaje
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. R. Jacobs
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. J. Schoenaers
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Editors and Affiliations

  1. Department of Oral Medicine, University of Washington, Seattle, Washington, USA

    J.K.M. Aps

  2. Gent, Belgium

    M. De Bruyne

  3. Department Beeldvorming & Pathologie - F, KU Leuven - OMFS-IMPATH Onderzoeksgroep, Leuven, Belgium

    R. Jacobs

  4. Praktijk voor Endodontologie, Zwolle, The Netherlands

    J. van der Meer

  5. MKA-chirurgie, Radboud UMC, Nijmegen, The Netherlands

    M.E.L. Nienhuijs

  6. Algemeen, Orthodontiepraktijktijk, Heerenveen, Friesland, The Netherlands

    S.C. Boxum

Copyright information

© 2016 Bohn Stafleu van Loghum

About this chapter

Cite this chapter

Politis, C., Agbaje, J., Jacobs, R., Schoenaers, J. (2016). Wondhelingsproblemen in de mond. In: Aps, J., De Bruyne, M., Jacobs, R., van der Meer, J., Nienhuijs, M., Boxum, S. (eds) Het tandheelkundig jaar 2017. Bohn Stafleu van Loghum, Houten. https://doi.org/10.1007/978-90-368-1030-2_3

Download citation

  • DOI: https://doi.org/10.1007/978-90-368-1030-2_3

  • Published:

  • Publisher Name: Bohn Stafleu van Loghum, Houten

  • Print ISBN: 978-90-368-1029-6

  • Online ISBN: 978-90-368-1030-2

  • eBook Packages: Dutch language eBook collection

Publish with us

Policies and ethics

Search

Navigation