Skip to main content

Other Secondary Peritoneal Surface Malignancies

  • Chapter
Treatment of Peritoneal Surface Malignancies

Part of the book series: Updates in Surgery ((UPDATESSURG))

  • 881 Accesses

Abstract

Patients with peritoneal metastasis (PM) are typically considered as having a terminal and incurable disease [1–3]. Since the late 1990s, a novel therapeutic approach, has emerged combining cytoreductive surgery (CRS) performed to treat all visible disease, plus hyperthermic intraperitoneal chemotherapy (HIPEC) used to treat microscopic residual disease [4, 5]. This treatment radically changed the therapeutic approach to patients with peritoneal surface malignancies and is regarded as the standard of care for pseudomyxoma peritonei from appendiceal cancer and peritoneal mesotheliomas [6, 7]. It also provides improved survival rates for treating PM from ovarian [8–10], gastric [11, 12], and colorectal cancers [13–15].

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 84.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Hardcover Book
USD 109.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. Gusani NG, Sung WC, Colovos C et al (2008) Aggressive surgical management of peritoneal carcinomatosis with low mortality in a high volume tertiary center. Ann surg oncol 15:654–663

    Article  Google Scholar 

  2. Chu DZ, Lang NP, Thomson C et al (1989) Peritoneal carcinomatosis in non gynecologic malignancies. A prospective study of prognostic factors. Cancer 63:364–367

    Article  CAS  PubMed  Google Scholar 

  3. Jayne DG, Fook S, Loi C et al (2002) Peritoneal carcinomatosis from colorectal cancer. Br J Surg 89:1545–1550

    Article  CAS  PubMed  Google Scholar 

  4. Sugarbaker PH, Cunliffe WJ, Beliveau JF et al (1988) Rationale for perioperative intraperitoneal chemotherapy as a surgical adjuvant for gastro-intestinal malignancies. Reg Cancer Treat 1:66–79

    Google Scholar 

  5. Sugarbaker PH (1988) Intraperitoneal chemotherapy and cytoreductive surgery for the prevention and treatment of peritoneal carcinomatosis and sarcomatosis. Semin Surg Oncol 14:254–261

    Article  Google Scholar 

  6. Chua T, Moran B, Sugarbaker PH (2012) Early and long-term outcome on 2298 patients with psudomyxoma peritonei of appendiceal origin treated by a strategy of cytoreductive surgery and hyperthermic intraperitoneal chemotherapy. J Clin Oncol 30:2449–2456

    Article  PubMed  Google Scholar 

  7. Yan TD, Deraco M, Baratti D (2009) Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy for malignant peritoneal mesothelioma: multi institutional experience. J Clin Oncol 27:6237–6242

    Article  PubMed  Google Scholar 

  8. Di Giorgio A, Naticchioni E, Biacchi D et al (2008) Cytoreductive surgery (peritonectomy procedures) combined with hyperthermic intraperitoneal chemotherapy (HIPEC) in the treatment of diffuse peritoneal carcinomatosis from ovarian cancer. Cancer 113:315–325

    Article  PubMed  Google Scholar 

  9. Chang SJ, Bristow R, Tyu HS (2012) Impact of complete cytoreduction leaving no gross residual disease associated with radical cytoreductive surgical procedures on survival in advanced ovarian cancer. Ann Surg Oncol 19:4059–4067

    Article  PubMed  Google Scholar 

  10. Helm WC (2012) Current status and future directions of cytoreductive surgery and HIPEC in the treatment of ovarian cancer. Surg Oncol Clin N Am 21:645–663

    Article  PubMed  Google Scholar 

  11. Yonemura Y, Kawamura T, Bardon E et al (2005) Treatment of peritoneal dissemination from gastric cancer by peritonectomy and chemo-hyperthermic peritoneal perfusion. Br J Surg 92:370–375

    Article  CAS  PubMed  Google Scholar 

  12. Glehen O, Gilly F, Arvieux C (2010) Peritoneal carcinomatosis from gastric cancer: a multi institutional study of 159 patients treated by cytoreductive surgery combined with perioperative intraperitoneal chemotherapy. Ann Surg Oncol 17:2370–2377

    Article  PubMed  Google Scholar 

  13. Verwaal VJ, Van Ruth S, de Bree E et al (2003) Randomized trial of cytoreduction and hyperthermic intraperitoneal chemotherapy versus systemic chemotherapy and palliative surgery in patients with peritoneal carcinomatosis of colorectal cancer. J Clin Oncol 21:3737–3743

    Article  PubMed  Google Scholar 

  14. Sammartino P, Sibio S, Biacchi D et al (2012) Prevention of peritoneal metastases from colon cancer in high risk patients: Preliminary results of surgery plus prophylactic HIPEC. Gastroenterol Res Pract 2012:141585

    Article  PubMed Central  PubMed  Google Scholar 

  15. Elias D, Lefevre JH, Chevalier J et al (2009) Complete cytoreductive surgery plus intraperitoneal chemo-hyperthermia with oxaliplatin for peritoneal carcinomatosis of colorectal origin. J Clin Oncol 27:681–685

    Article  PubMed  Google Scholar 

  16. Glehen O, Osinski D, Baujard AL et al (2003) Natural history of peritoneal carcinomatosis from non gynecological malignancies. Surg Oncol Clin N Am 12:729–739

    Article  PubMed  Google Scholar 

  17. Carmignani CP, Sugarbaker TH, Bromley CN (2003) Intraperitoneal cancer dissemination: mechanism of patterns of spread. Cancer Metastasis Rev 22:4105–4172

    Article  Google Scholar 

  18. Elias D, David A, Sourrouille I et al (2013) Neuroendocrine carcinomas: optimal surgery of peritoneal metastasis (and associated intra-abdominal metastasis). Surgery (in press) http://dx.doi.org/10.106/jsurg 2013.05.030

    Google Scholar 

  19. Munene G, Lloyd A, Temple WJ (2011) Systematic review of the efficacy of multimodal treatment of sarcomatosis with cytoreduction and intraperitoneal chemotherapy. Ann Surg Oncol 18:207–213

    Article  PubMed  Google Scholar 

  20. Baratti D, Pennacchioli E, Kusamura S et al (2012) Peritoneal sarcomatosis: is there subset of patients who may benefit from cytoreductive surgery and hyperthermic intraperitoneal chemotherapy. Ann Surg Oncol 17:3220–3228

    Article  Google Scholar 

  21. Kalliampust AA, Shukla NK, Deo SV et al (2012) Updates on the multimodality management of desmoplastic small round cell tumors. J Surg Oncol 105:617–621

    Article  Google Scholar 

  22. Abu-Rustum NR, Aghajanian CA, Venkatraman ES et al (1997) Metastatic breast carcinoma to the abdomen and pelvis. Gynecol Oncol 66:41–44

    Article  CAS  PubMed  Google Scholar 

  23. Parker SL, Tong T, Bolden S et al (1996) Cancer statistics 1996, CA. Cancer J Clin 46:5–27

    Article  CAS  Google Scholar 

  24. Tuthill M, Pell R, Giuliani R et al (2009) Peritoneal disease in breast cancer: A specific entity with an extremely poor prognosis. Eur J Cancer 45:2146–2149

    Article  PubMed  Google Scholar 

  25. Saunders Y, Stebbing J, Broadley K et al (2001) Recurrent locally advanced breast cancer. The treatment of chest wall disease with further chemotherapy. Clin Oncol (R Coll Radiol) 13:195–199

    CAS  Google Scholar 

  26. Stebbing J, Crane J, Gaya A (2006) Breast cancer (metastatic). Clin Evid 15:2331–2359

    PubMed  Google Scholar 

  27. Eitan R, Gemignani ML, Verkatraman ES et al (2003) Breast cancer metastatic to abdomen and pelvis. Role of surgical resection. Gynecol Oncol 90:397–401

    Article  PubMed  Google Scholar 

  28. Cardi M, Sammartino P, Framarino ML et al (2013) Treatment of peritoneal carcinomatosis from breast cancer by maximal cytoreduction and HIPEC : a preliminary report on 5 cases. Breast 22:845–849

    Article  PubMed  Google Scholar 

  29. Sheen-Chen SM, Liu YW, Sun CK et al (2008) Abdominal carcinomatosis attributed to metastatic breast carcinoma. Dig Dis Sci 53:3043–3045

    Article  PubMed  Google Scholar 

  30. Tornos C, Soslow R, Chen S et al (2005) Expression of WT1, Ca125 and GCDFP-15 as useful markers in the differential diagnosis of primary ovarian carcinomatosis versus metastatic breast cancer to the ovary. Am J Surg Pathol 20:1482–1489

    Article  Google Scholar 

  31. Disario JA, Burt BW, Vargas H et al (1994) Small bowel cancer: epidemiological and clinical characteristics from population-based registry. Am J Gastroenterol 89:699–701

    CAS  PubMed  Google Scholar 

  32. Marchettini P, Sugarbaker PH (2002) Mucinous adenocarcinoma of the small bowel with peritoneal seeding. Case report and review of the literature. Eur J Surg Oncol 28:19–23

    Article  CAS  PubMed  Google Scholar 

  33. Chua TC, Kohl JL, Yan TD et al (2009) Cytoreductive surgery and perioperative intraperitoneal chemotherapy for peritoneal carcinomatosis from small bowel adenocarcinoma. J Surg Oncol 100:139–143

    Article  PubMed  Google Scholar 

  34. Shen P, Stewart JH 4th, Levine EA (2009) Cytoreductive surgery and intraperitoneal hyperthermic chemotherapy for peritoneal surface malignancy: non colorectal indications. Curr Probl Cancer 33:168–193

    Article  PubMed  Google Scholar 

  35. Glehen O, Elias D, Gilly FN (2008) Presentation du rapport de l’Association Francaise de Chirurgie. In: Elias D, Gilly EN, Glehen O Eds. Carcinoses peritoneales d’origine digestive et primitives. France. Arnette Walkers Kluwer, pp.101–152

    Google Scholar 

  36. Delotte J, Desantis M, Frigenza M et al (2014) Cytoreductive surgery with hyperthermic intraperitoneal chemotherapy for the treatment of endometrial cancer with peritoneal carcinomatosis. Eur J Obstet Gynocol Reprod Biol 172:111–114

    Article  Google Scholar 

  37. Bakrin N, Cotte E, Sayag-Beaugard A et al (2010) Cytoreductive surgery with hyperthermic intraperitoneal chemotherapy for the treatment of recurrent endometrial carcinoma confined to the peritoneal cavity. Int J Gynecol Cancer 20:809–814

    Article  PubMed  Google Scholar 

  38. Glehen O, Gilly F, Bouttle F et al (2010) Toward curative treatment of peritoneal carcinomatosis from non-ovarian origin by cytoreductive surgery combined with perioperative intraperitoneal chemotherapy. Cancer 16:5608–5618

    Article  Google Scholar 

  39. Kerscher AG, Mallalieu J, Pitroff A et al (2010) morbidity and mortality of 109 consecutive cytoreductive procedures with hyperthermic intraperitoneal chemotherapy (HIPEC) performed at a community hospital. World J Surg 34:62–69

    Article  PubMed  Google Scholar 

  40. Levine EA, Stewart JH, Shin P et al (2014) Intraperitoneal chemotherapy from peritoneal surface malignancy : experience with 1000 patient. J Am Coll Surg 218:573–587

    Article  PubMed  Google Scholar 

  41. Turrini O, Lambaudie E, Faucher M et al (2012) Initial experience with hyperthermic intraperitoneal chemotherapy. Arch Surg 147:919–923

    Article  CAS  PubMed  Google Scholar 

  42. Yoon W, Alame A, Beni R (2014) Peritoneal surface disease severity score as a predictor of resectability in the treatment of peritoneal surface malignancies. Am J Surg 207:403–407

    Article  PubMed  Google Scholar 

  43. Votanopoulos KI, Newman NA, Russel G et al (2013) Outcomes of cytoreductive surgery (CRS) with hyperthermic intraperitoneal chemotherapy (HIPEC) in patients older than 70 years: survival benefits at considerable morbidity and mortality. Ann Surg Oncol 20:3497–3503

    Article  PubMed  Google Scholar 

  44. Sun Y, Chen P, Stewart JH et al (2013) Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy for peritoneal carcinomatosis from small bowel adenocarcinoma. Am Surg 79:644–648

    PubMed Central  PubMed  Google Scholar 

  45. Jacks SP, Hundley JC, Shen P et al (2005) Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy for peritoneal carcinomatosis from small bowel adenocarcinoma. J Surg Oncol 9:112–17

    Article  Google Scholar 

  46. Randle RW, Swett KR, Shen P et al (2013) Cytoreductive surgery with hyperthermic intraperitoneal chemotherapy in peritoneal sarcomatosis. Am Surg 6:620–4

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Maurizio Cardi .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2015 Springer-Verlag Italia

About this chapter

Cite this chapter

Cardi, M., Atta, J.M.F., Mingarelli, V., Naticchioni, E., Biacchi, D., Di Giorgio, A. (2015). Other Secondary Peritoneal Surface Malignancies. In: Di Giorgio, A., Pinto, E. (eds) Treatment of Peritoneal Surface Malignancies. Updates in Surgery. Springer, Milano. https://doi.org/10.1007/978-88-470-5711-1_22

Download citation

  • DOI: https://doi.org/10.1007/978-88-470-5711-1_22

  • Publisher Name: Springer, Milano

  • Print ISBN: 978-88-470-5710-4

  • Online ISBN: 978-88-470-5711-1

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics