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Other Primary Peritoneal Surface Malignancies

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Treatment of Peritoneal Surface Malignancies

Part of the book series: Updates in Surgery ((UPDATESSURG))

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Abstract

Primary peritoneal surface malignancies (other than mesothelioma) are serous papillary carcinoma (PPSPC) and desmoplastic small round cell tumor (DSRCT). According new histogenetic theories, PPSPC and ovarian cancer (OC) originate from the tubal epithelium. Primary treatment in foreseen as being the application of maximal cytoreduction (peritonectomy procedures) combined with hyperthermic intraperitoneal chemotherapy (HIPEC). Evaluation of results must be done using the staging system comprising Peritoneal Cancer Index (PCI) and Completeness of Cytoreduction (CC) score. DSRCT is a rare and aggressive neoplasm, and patients typically present with an advanced stage with multiple peritoneal-based lesions. Despite multiple therapeutic strategies that include chemotherapy, aggressive debulking surgery, and abdominal-wall radiation, durable remission remains rare. A new staging system is proposed by the MD Anderson Cancer Center in the US, where peritonectomy procedures plus HIPEC are being applied with interesting results.

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Authors and Affiliations

  1. Department of Surgery “Pietro Valdoni”, Sapienza University of Rome, Rome, Italy

    Paolo Sammartino

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  1. Paolo Sammartino
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  2. Fabio Accarpio
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  3. Tommaso Cornali
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  4. Alessio Impagnatiello
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  5. Bianca Maria Sollazzo
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  6. Maria Luisa Framarino dei Malatesta
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Correspondence to Paolo Sammartino .

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Editors and Affiliations

  1. Department of Surgery “Pietro Valdoni”, Sapienza University of Rome, Rome, Italy

    Angelo Di Giorgio

  2. Department of Medical, Surgical, and Neurological Sciences, University of Siena, Siena, Italy

    Enrico Pinto

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Sammartino, P., Accarpio, F., Cornali, T., Impagnatiello, A., Sollazzo, B.M., dei Malatesta, M.L.F. (2015). Other Primary Peritoneal Surface Malignancies. In: Di Giorgio, A., Pinto, E. (eds) Treatment of Peritoneal Surface Malignancies. Updates in Surgery. Springer, Milano. https://doi.org/10.1007/978-88-470-5711-1_21

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  • DOI: https://doi.org/10.1007/978-88-470-5711-1_21

  • Publisher Name: Springer, Milano

  • Print ISBN: 978-88-470-5710-4

  • Online ISBN: 978-88-470-5711-1

  • eBook Packages: MedicineMedicine (R0)

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