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MR Findings in Crohn’s Disease

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MR Enterography

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Abstract

Inflammatory bowel disease (IBD) primarily refers to two chronic diseases that cause chronic inflammation of all or part of the digestive tract: ulcerative colitis (UC) and Crohn’s disease (CD).

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References

  1. Martin DR, Lauenstein T, Sitaraman SV (2007) Utility of magnetic resonance imaging in small bowel Crohn’s disease. Gastroenterology 133:385–390

    Article  PubMed  Google Scholar 

  2. Satsangi J, Parkes M, Jewell DP et al (1998) Genetics of inflammatory bowel disease. Clin Sci (Lond) 94:473–478

    CAS  Google Scholar 

  3. Loftus EV Jr (2004) Clinical epidemiology of inflammatory bowel disease: incidence, prevalence, and environmental influences. Gastroenterology 126:1504–1517

    Article  PubMed  Google Scholar 

  4. Shanahan F (2002) Crohn’s disease. Lancet 359:62–69

    Article  CAS  PubMed  Google Scholar 

  5. Wills JS, Lobis IF, Denstman FJ (1997) Crohn disease: state of the art. Radiology 202:597–610

    CAS  PubMed  Google Scholar 

  6. Podolsky DK (2002) Inflammatory bowel disease. N Engl J Med 347:417–429

    Article  CAS  PubMed  Google Scholar 

  7. Bosani M, Ardizzone S, Porro GB (2009) Biologic targeting in the treatment of inflammatory bowel diseases. Biologics 3:77–97

    CAS  PubMed Central  PubMed  Google Scholar 

  8. Bansal P, Sonnenberg A (1996) Risk factors for colorectal cancer in inflammatory bowel disease. Am J Gastroenterol 91:44–48

    CAS  PubMed  Google Scholar 

  9. Cheifetz AS (2013) Management of active Crohn disease. JAMA 309:2150–2158

    Article  CAS  PubMed  Google Scholar 

  10. Del Vescovo R, Sansoni I, Caviglia R et al (2008) Dynamic contrast enhanced magnetic resonance imaging of the terminal ileum: differentiation of activity of Crohn’s disease. Abdom Imaging 33:417–424

    Article  PubMed  Google Scholar 

  11. Gourtsoyiannis NC, Grammatikakis J, Papamastorakis G et al (2006) Imaging of small intestinal Crohn’s disease: comparison between MR enteroclysis and conventional enteroclysis. Eur Radiol 16:1915–1925

    Article  PubMed  Google Scholar 

  12. Masselli G, Brizi G, Parrella A et al (2004) Crohn disease magnetic resonance enteroclysis. Abdom Imaging 29:326–334

    Article  CAS  PubMed  Google Scholar 

  13. Chou CK, Chen LT, Sheu RS et al (1994) MRI manifestations of gastrointestinal wall thickening. Abdom Imaging 19:389–394

    Article  CAS  PubMed  Google Scholar 

  14. Prassopoulos P, Papanikolaou N, Grammatikakis J et al (2001) MR enteroclysis imaging of Crohn disease. Radiographics 21:s161–s172

    Article  PubMed  Google Scholar 

  15. Maselli G, Casciani E, Polettini et al (2006) Assessment of Crohn’s disease in the small bowel: prospective comparison of magnetic resonance enteroclysis with conventional enteroclysis. Eur Radiol 16:2817–2827

    Article  Google Scholar 

  16. Mazziotti S, Ascenti G, Scribano E et al (2011) Guide to magnetic resonance in Crohn's disease: from common findings to the more rare complicances. Inflamm Bowel Dis 17:1209–1222

    Article  PubMed  Google Scholar 

  17. Tolan JM, Greenhalgh R, Zealley IA et al (2010) MR enterographic manifestation of small bowel Crohn disease. Radiographics 30:367–384

    Article  PubMed  Google Scholar 

  18. Sempere GA, Martinez SV, Medina CE (2005) MRI evaluation of inflammatory activity in Crohn’s disease. Am J Roentgenol 184:1829–1835

    Article  Google Scholar 

  19. Zappa M, Stefanescu C, Cazals-Hatem D et al (2011) Which magnetic resonance findings accurately evaluate inflammation in small bowel Crohn’s disease? A retrospective comparison with surgical pathologic analysis. Inflamm Bowel Dis 17:984–993

    Article  PubMed  Google Scholar 

  20. Griffin N, Grant LA, Anderson S et al (2012) Small bowel MR enterography: problem solving in Crohn’s disease. Insights Imaging 3:251–263

    Article  PubMed Central  PubMed  Google Scholar 

  21. Sinha R, Murphy P, Hawker P et al (2009) Role of MRI in Crohn’s disease. Clin Radiol 64:341–352

    Article  CAS  PubMed  Google Scholar 

  22. Oto A, Kulkarni K, Karczmar GS et al (2009) Evaluation of diffusion-weighted MR imaging for detection of bowel inflammation in patients with Crohn’s disease. Acad Radiol 16:597–603

    Article  PubMed Central  PubMed  Google Scholar 

  23. Kiryu S, Dodanuki K, Takao H et al (2009) Free-breathing diffusion-weighted imaging for the assessment of inflammatory activity in Crohn’s disease. J Magn Reson Imaging 29:880–886

    Article  PubMed  Google Scholar 

  24. Buisson A, Joubert A, Montoriol PF et al (2013) Diffusion-weighted magnetic resonance imaging for detecting and assessing ileal inflammation in Crohn’s disease. Aliment Pharmacol Ther 37:537–545

    Article  CAS  PubMed  Google Scholar 

  25. Froelich JM, Waldherr C, Stoupis C et al (2010) MR motility in Crohn’s disease improves lesion detection compared with standard MR imaging. Eur Radiol 20:1945–1951

    Article  Google Scholar 

  26. Odille F, Menys A, Ahmed A et al (2012) Quantitative assessment of small bowel motility by nonrigid registration of dynamic MR images. Magn Reson Med 68:783–793

    Article  PubMed  Google Scholar 

  27. Menys A, Atkinson D, Odille F et al (2012) Quantified terminal ileal motility during MR enterography as a potential biomarker of Crohn’s disease activity: a preliminary study. Eur Radiol 22:2494–2501

    Article  PubMed  Google Scholar 

  28. Yacoub HJ, Obara P, Oto A (2013) Evolving role of MRI in Crohn’s disease. J Magn Reson Imaging 37:1277–1289

    Article  PubMed  Google Scholar 

  29. Sinha R, Rajia P, Murphy P et al (2009) Utility of high-resolution MR imaging in demonstrating transmural pathologic changes in Crohn disease. Radiographics 29:1847–1867

    Article  PubMed  Google Scholar 

  30. Sinha R, Murphy P, Sanders S et al (2013) Diagnostic accuracy of high-resolution MR enterography in Crohn’s disease: comparison with surgical and pathological specimen. Clin Radiol 68:917–927

    Article  CAS  PubMed  Google Scholar 

  31. Laghi A, Paolantonio P, Catalano C et al (2003) MR imaging of the small bowel using polyethylene glycol solution as an oral contrast agent in adults and children with celiac disease: preliminary observations. Am J Roentgenol 180:191–194

    Article  Google Scholar 

  32. Low RN, Francis IR, Politoske D et al (2000) Crohn’s disease evaluation: comparison of contrast-enhanced MR imaging and single-phase helical CT scanning. J Magn Reson Imaging 11:127–135

    Article  CAS  PubMed  Google Scholar 

  33. Maccioni F, Viscido A, Broglia L et al (2000) Evaluation of Crohn disease activity with magnetic resonance imaging. Abdom Imaging 25:219–228

    Article  CAS  PubMed  Google Scholar 

  34. Laghi A, Borrelli O, Paolantonio P et al (2003) Contrast enhanced magnetic resonance imaging of the terminal ileum in children with Crohn’s disease. Gut 52:393–397

    Article  CAS  PubMed Central  PubMed  Google Scholar 

  35. Taylor SA, Punwani S, Rodriguez-Justo M et al (2009) Mural Crohn disease: correlation of dynamic contrast-enhanced MR imaging findings with angiogenesis and inflammation at histologic examination. Pilot study. Radiology 251:369–379

    Article  PubMed  Google Scholar 

  36. Giusti S, Faggioni L, Neri E et al (2010) Dynamic MRI of the small bowel: usefulness of quantitative contrast-enhancement parameters and time-signal intensity curves for differentiating between active and inactive Crohn’s disease. Abdom Imaging 35:646–653

    Article  PubMed  Google Scholar 

  37. Oto A, Fan X, Mustafi D et al (2009) Quantitative analysis of dynamic contrast enhanced MRI for assessment of bowel inflammation in Crohn’s disease: pilot study. Acad Radiol 16:1223–1230

    Article  PubMed  Google Scholar 

  38. Maccioni F, Bruni A, Viscido A et al (2006) MR imaging in patients with Crohn disease: MR sequences with the use of an oral superparamagnetic contrast agent. Radiology 238:157–530

    Article  Google Scholar 

  39. Gourtsoyianni S, Papanikolaou N, Amanakis E et al (2009) Crohn’s disease lymphadenopathy: MR imaging findings. Eur J Radiol 69:425–428

    Article  PubMed  Google Scholar 

  40. Gasche C, Scholmerich J, Brynskov J et al (2000) A simple classification of Crohn’s disease: report of the Working Party for the world Congress of Gastroenterology, Vienna 1998. Inflamm Bowel Dis 6:8–15

    Article  CAS  PubMed  Google Scholar 

  41. Satsangi J, Silverberg MS, Vermeire S et al (2006) The Montreal classification of inflammatory bowel disease: controversies, consensus, and implications. Gut 55:749–753

    Article  CAS  PubMed Central  PubMed  Google Scholar 

  42. Leyendecker JR, Bloomfeld RS, DiSantis DF et al (2009) MR enterography in the management of patients with Crohn disease. Radiographics 29:1827–1846

    Article  PubMed  Google Scholar 

  43. Schmidt S, Chevvalier P, Bessoud B et al (2007) Diagnostic performance of MRI for detection of intestinal fistulas in patients with complicated inflammatory conditions. Eur Radiol 17:2957–2963

    Article  CAS  PubMed  Google Scholar 

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Authors and Affiliations

  1. Department of Radiological Sciences, University of Messina, Messina, Italy

    Silvio Mazziotti & Alfredo Blandino

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  1. Silvio Mazziotti
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  2. Alfredo Blandino
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Mazziotti, S., Blandino, A. (2014). MR Findings in Crohn’s Disease. In: MR Enterography. Springer, Milano. https://doi.org/10.1007/978-88-470-5675-6_4

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  • DOI: https://doi.org/10.1007/978-88-470-5675-6_4

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  • Publisher Name: Springer, Milano

  • Print ISBN: 978-88-470-5670-1

  • Online ISBN: 978-88-470-5675-6

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