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Pulmonary Functional Imaging with Positron Emission Tomography

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Mechanics of Breathing

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Abstract

In most diseases of the lung, both function and structure are spatially heterogeneous. As a result, global measures of lung function obtained from measurements at the mouth may be insensitive to localized pathological changes in the lungs and usually fail to detect the true extent of the functional impairment. With the development of imaging methods capable of providing detailed information in three dimensions, the field of functional imaging has emerged to fill these gaps.

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Notes

  1. 1.

    If the duration of the apnea is very short, the kinetics may not exhibit a plateau. In this case, Q A can be estimated by extrapolating an exponential function fitted to the apnea curve.

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Authors and Affiliations

  1. Department of Anesthesia, Pain Medficine and Critical Care, Massachusetts General Hospital, Boston, MA, 01907, USA

    Jose G. Venegas, Dominic Layfield, Scott Harris, Elliot Greenblatt & Tilo Winkler

Authors
  1. Jose G. Venegas
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  2. Dominic Layfield
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  3. Scott Harris
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  4. Elliot Greenblatt
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  5. Tilo Winkler
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Corresponding author

Correspondence to Jose G. Venegas .

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Editors and Affiliations

  1. Politecnico di Milano, Milano, Italy

    Andrea Aliverti

  2. Politecnico di Milano, Milano, Italy

    Antonio Pedotti

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Venegas, J.G., Layfield, D., Harris, S., Greenblatt, E., Winkler, T. (2014). Pulmonary Functional Imaging with Positron Emission Tomography. In: Aliverti, A., Pedotti, A. (eds) Mechanics of Breathing. Springer, Milano. https://doi.org/10.1007/978-88-470-5647-3_19

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  • DOI: https://doi.org/10.1007/978-88-470-5647-3_19

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