Skip to main content

Contrast-Enhanced Intraoperative Ultrasound Using Liver-Specific Contrast Agents

  • Chapter
  • First Online:
Book cover Ultrasound-Guided Liver Surgery
  • 1926 Accesses

Abstract

As already described in the former chapters, the technique of liver surgery has substantially improved over the past few decades, partially because of the invention of IOUS [1].

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 79.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 99.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 129.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. Makuuchi M, Hasegawa H, Yamazaki S, Takayasu K, Moriyama N (1987) The use of operative ultrasound as an aid to liver resection in patients with hepatocellular carcinoma. World J Surg 11(5):615–621

    Article  CAS  PubMed  Google Scholar 

  2. Yanagisawa K, Moriyasu F, Miyahara T, Yuki M, Iijima H (2007) Phagocytosis of ultrasound contrast agent microbubbles by Kupffer cells. Ultrasound Med Biol 33(2):318–325

    Article  PubMed  Google Scholar 

  3. Kindberg GM, Tolleshaug H, Roos N, Skotland T (2003) Hepatic clearance of Sonazoid perfluorobutane microbubbles by Kupffer cells does not reduce the ability of liver to phagocytose or degrade albumin microspheres. Cell Tissue Res 312(1):49–54

    PubMed  Google Scholar 

  4. Hatanaka K, Kudo M, Minami Y et al (2008) Differential diagnosis of hepatic tumors: value of contrast-enhanced harmonic sonography using the newly developed contrast agent. Sonazoid Intervirol 51(Suppl 1):61–69

    Article  Google Scholar 

  5. Watanabe R, Matsumura M, Chen CJ, Kaneda Y, Ishihara M, Fujimaki M (2003) Gray-scale liver enhancement with Sonazoid (NC100100), a novel ultrasound contrast agent; detection of hepatic tumors in a rabbit model. Biol Pharm Bull 26(9):1272–1277

    Article  CAS  PubMed  Google Scholar 

  6. Kudo M (2008) Hepatocellular carcinoma 2009 and beyond: from the surveillance to molecular targeted therapy. Oncology 75(Suppl 1):1–12

    Article  CAS  PubMed  Google Scholar 

  7. Torzilli G, Palmisano A, Del Fabbro D et al (2007) Contrast-enhanced intraoperative ultrasonography during surgery for hepatocellular carcinoma in liver cirrhosis: is it useful or useless? A prospective cohort study of our experience. Ann Surg Oncol 14(4):1347–1355

    Article  PubMed  Google Scholar 

  8. Arita J, Takahashi M, Hata S et al (2011) Usefulness of contrast-enhanced intraoperative ultrasound using sonazoid in patients with hepatocellular carcinoma. Ann Surg 254(6):992–999

    Article  PubMed  Google Scholar 

  9. Simmonds PC, Primrose JN, Colquitt JL, Garden OJ, Poston GJ, Rees M (2006) Surgical resection of hepatic metastases from colorectal cancer: a systematic review of published studies. Br J Cancer 94(7):982–999

    Article  CAS  PubMed Central  PubMed  Google Scholar 

  10. Nakano H, Ishida Y, Hatakeyama T et al (2008) Contrast-enhanced intraoperative ultrasonography equipped with late Kupffer-phase image obtained by sonazoid in patients with colorectal liver metastases. World J Gastroenterol 14(20):3207–3211

    Article  PubMed Central  PubMed  Google Scholar 

  11. Takahashi M, Hasegawa K, Arita J et al (2012) Contrast-enhanced intraoperative ultrasonography using perfluorobutane microbubbles for the enumeration of colorectal liver metastases. Br J Surg 99(9):1271–1277

    Article  CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Junichi Arita .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2014 Springer-Verlag Italia

About this chapter

Cite this chapter

Arita, J., Kokudo, N. (2014). Contrast-Enhanced Intraoperative Ultrasound Using Liver-Specific Contrast Agents. In: Torzilli, G. (eds) Ultrasound-Guided Liver Surgery. Springer, Milano. https://doi.org/10.1007/978-88-470-5510-0_6

Download citation

  • DOI: https://doi.org/10.1007/978-88-470-5510-0_6

  • Published:

  • Publisher Name: Springer, Milano

  • Print ISBN: 978-88-470-5509-4

  • Online ISBN: 978-88-470-5510-0

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics