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Alemtuzumab

  • Giuseppe Tridente
Chapter

Abstract

Alemtuzumab (Campath®, MabCampath®, Genzyme) is an IgG1k anti-CD52 humanized monoclonal antibody (mAb) that was first licensed in March 2001 by FDA. EMEA granted its approval in July 2001 and Health Canada in November 2005. The initial indication was limited to B-CLL previously treated and resistant to alkylating agents. Starting from 2007, alemtuzumab was approved also as first-line therapy of B-CLL. So far, it has been experienced in over 60 countries.

Keywords

Progressive Multifocal Leukoencephalopathy Infusion Reaction Progressive Multifocal Leukoencephalopathy Tumor Lysis Syndrome Cytokine Release Syndrome 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Supplementary material

307171_1_En_7_MOESM1_ESM.xls (59 kb)
Supplementary material 1 (XLS 60 kb)

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Copyright information

© Springer-Verlag Italia 2014

Authors and Affiliations

  1. 1.University of VeronaVeronaItaly

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