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Rilonacept

  • Giuseppe TridenteEmail author
Chapter

Abstract

Rilonacept (Arcalyst®, Regeneron) is a dimeric fusion protein combining the extracellular portion of human interleukin Type I receptor (IL.1RI) and the IL-1 receptor accessory protein (IL-1RAcP) with the Fc portion of human IgG1. Acting as a decoy receptor for both IL-1α and IL-1β, rilonacept inhibits their interaction with the natural receptors and therefore the expression of the consequent bioactivity of the bound cytokines.

Keywords

Familial Mediterranean Fever Orphan Drug Actinic Keratosis Injection Site Reaction Familial Mediterranean Fever Patient 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag Italia 2014

Authors and Affiliations

  1. 1.University of VeronaVeronaItaly

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