Alefacept (Amevive®, Astellas) is a recombinant dimeric fusion protein combining the Fc fragment of human IgG1 with the CD2-binding portion of the human leukocyte antigen-3 (LFA-3).
KeywordsHypersensitivity Reaction Human IgG1 Plaque Psoriasis Injection Site Reaction Chronic Plaque Psoriasis
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- 1.Alefacept (Amevive®) Prescribing Information Astella, May 2012Google Scholar
- 2.Bhutani T, Kamangar F, Zitelli K et al (2012) Intralesional injections of alefacept may predict systemic response to intramuscular alefacept: results from a pilot study. J Dermatol Treat doi: 10.3109/09546634.2012.672712
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