• Giuseppe TridenteEmail author


Alefacept (Amevive®, Astellas) is a recombinant dimeric fusion protein combining the Fc fragment of human IgG1 with the CD2-binding portion of the human leukocyte antigen-3 (LFA-3).


Hypersensitivity Reaction Human IgG1 Plaque Psoriasis Injection Site Reaction Chronic Plaque Psoriasis 
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    Alefacept (Amevive®) Prescribing Information Astella, May 2012Google Scholar
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    Bhutani T, Kamangar F, Zitelli K et al (2012) Intralesional injections of alefacept may predict systemic response to intramuscular alefacept: results from a pilot study. J Dermatol Treat doi: 10.3109/09546634.2012.672712
  3. 3.
    Lui H, Gulliver W, Hong TJ et al (2012) A randomized controlled study of combination therapy with alefacept and narrow band UVB phototherapy (UVB) for moderate to severe psoriasis: efficacy, onset, and duration of response. J Drugs Dermatol 11:929–937PubMedGoogle Scholar

Copyright information

© Springer-Verlag Italia 2014

Authors and Affiliations

  1. 1.University of VeronaVeronaItaly

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