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Ranibizumab

  • Giuseppe TridenteEmail author
Chapter

Abstract

Ranibizumab (Lucentis®, Genentech, Novartis) is a recombinant humanized IgG1k monoclonal Fab fragment binding to human vascular endothelial growth factor-A (VEGF-A). In June 2006, FDA approved ranibizumab for intravitreal (IVI) treatment of neovascular age-related (wet) macular degeneration (AMD). In March 2007, EMEA granted approval for the same indication. In June 2010, on the basis of additional data, FDA extended the indication to macular edema following retinal vein occlusion (RVO), and in October 2012 to the treatment of patients with diabetic macular edema (DME).

Keywords

Intravitreal Injection Macular Hole Diabetic Macular Edema Retinal Vein Occlusion Cystoid Macular Edema 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Supplementary material

307171_1_En_34_MOESM1_ESM.xls (71 kb)
Supplementary material 1 (XLS 72 kb)

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Copyright information

© Springer-Verlag Italia 2014

Authors and Affiliations

  1. 1.University of VeronaVeronaItaly

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