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Bevacizumab

  • Giuseppe Tridente
Chapter

Abstract

Bevacizumab (Avastin®, Genentec) is a recombinant humanized monoclonal IgG1k antibody specifically binding to soluble vascular endothelial growth factor (VEGF-A), and thus inhibiting its interaction with the respective receptors Flt-1 (VEGFR-1), KDR (VEGFR-2), and Ftl-4 (VEGF-3) located at the surface of endothelial cells.

Keywords

Vascular Endothelial Growth Factor Epithelial Ovarian Cancer Cystoid Macular Edema mCRC Patient Vascular Endothelial Growth Factor Signaling 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Supplementary material

307171_1_En_10_MOESM1_ESM.xls (56 kb)
Supplementary material 1 (XLS 57 kb)

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Copyright information

© Springer-Verlag Italia 2014

Authors and Affiliations

  1. 1.University of VeronaVeronaItaly

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