Abstract
Traditionally, planar bone scintigraphy (PS) is a very sensitive technique regarding the detection of bone lesions, but specificity is limited. In most cases PS is sufficient to exclude or detect bone metastases in tumor patients. Experienced nuclear physicians are able to differentiate degenerative from malignant lesions because of the intensity and localization of radionuclide uptake in the majority of examinations. Additional performance of single photon emission computed tomography (SPECT) increases the sensitivity of bone scintigraphy. In focal lesions that are not clear on planar or SPECT images, a supplementary SPECT/CT examination can provide a definite diagnosis in approximately 90% of lesions [1–3] (Figs. 1, 2). SPECT/CT is especially helpful in assessing lesions of the axial skeleton (Fig. 3).
Keywords
- Single Photon Emission Compute Tomography
- Bone Lesion
- Focal Lesion
- Single Photon Emission Compute Tomography Image
- Iodine Contrast Material
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
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References
Even-Sapir E, Metser U, Mishani E et al (2006) The detection of bone metastases in patients with high-risk prostate cancer: 99mTc-MDP Planar bone scintigraphy, single-and multi-field-of-view SPECT, 18F-fluoride PET, and 18F-fluoride PET/CT. J Nucl Med 47:287–297
Strobel K, Burger C, Seifert B (2007) Characterization of focal bone lesions in the axial skeleton: performance of planar bone scintigraphy compared with SPECT and SPECT fused with CT. AJR Am J Roentgenol 188:W467–474
Utsunomiya D, Shiraishi S, Imuta M et al (2006) Added value of SPECT/CT fusion in assessing suspected bone metastasis: comparison with scintigraphy alone and nonfused scintigraphy and CT. Radiology 238:264–271
Abe K, Sasaki M, Kuwabara Y et al (2005) Comparison of 18FDG-PET with 99mTc-HMDP scintigraphy for the detection of bone metastases in patients with breast cancer. Ann Nucl Med 19:573–579
Pagenstert GI, Barg A, Leumann AG et al (2009) SPECT-CT imaging in degenerative joint disease of the foot and ankle. J Bone Joint Surg Br 91:1191–1196
Huellner MW, Burkert A, Schleich FS et al (2012) SPECT/CT versus MRI in patients with nonspecific pain of the hand and wrist — a pilot study. Eur J Nucl Med Mol Imaging 39:750–759
Huellner M W, Strobel K, Hug U et al (2012) SPECT/CT in diagnostics of the hand joint. Radiologe 52:621–628
Schleich FS, Schurch M, Huellner MW et al (2012) Diagnostic and therapeutic impact of SPECT/CT in patients with unspecific pain of the hand and wrist. EJNMMI research 2:53
Strobel K, Steurer-Dober I, Huellner MW et al (2012) Importance of SPECT/CT for knee and hip joint prostheses. Radiologe 52:629–635
Bolouri C, Merwald M, Huellner MW et al (2012) Performance of orthopantomography, planar scintigraphy, CT alone and SPECT/CT in patients with suspected osteomyelitis of the jaw. Eur J Nucl Med Mol Imaging. Epub ahead of print
Strobel K, Merwald M, Huellner MW et al (2012) Importance of SPECT/CT for resolving diseases of the jaw. Radiologe 52:638–645
Kruger T, Hug U, Hullner MW et al (2011) SPECT/CT arthrography of the wrist in ulnocarpal impaction syndrome. Eur J Nucl Med Mol Imaging 38:792
Strobel K, Wiesmann R, Tornquist K et al (2012) SPECT/CT arthrography of the knee. Eur J Nucl Med Mol Imaging 39:1975–1976
Graute V, Feist M, Lehner S et al (2010) Detection of lowgrade prosthetic joint infections using 99mTc-antigranulo-cyte SPECT/CT: initial clinical results. Eur J Nucl Med Mol Imaging 37:1751–1759
Klaeser B, Spanjol M, Krause T (2012) SPECT/CT diagnostics for skeletal infections. Radiologe 52:615–620
Filippi L, Schillaci O (2006) SPECT/CT with a hybrid camera: a new imaging modality for the functional anatomical mapping of infections. Expert review of medical devices 3:699–703
Filippi L, Schillaci O (2006) Usefulness of hybrid SPECT/CT in 99mTc-HMPAO-labeled leukocyte scintigraphy for bone and joint infections. J Nucl Med 47:1908–1913
Filippi L, Uccioli L, Giurato L, Schillaci O (2009) Diabetic foot infection: usefulness of SPECT/CT for 99mTc-HMPAO-labeled leukocyte imaging. J Nucl Med 50:1042–1046
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Strobel, K. (2013). CT Specifies Bone Lesions in SPECT/CT. In: Hodler, J., von Schulthess, G.K., Zollikofer, C.L. (eds) Musculoskeletal Diseases 2013–2016. Springer, Milano. https://doi.org/10.1007/978-88-470-5292-5_27
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DOI: https://doi.org/10.1007/978-88-470-5292-5_27
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