Background
Crohn’s disease is a chronic granulomatous inflammatory disease of the gastrointestinal tract. According to epidemiological studies, the pathology is not uncommon, with 400,000–600,000 people affected in North America alone [1]. The disease occurs in males and females with the same prevalence; the peak age range of disease development is 15–25 years. The etiology is multifactorial but a familial tendency has been described, with an increased risk in first-degree relatives [1–3]. While many new clinical and surgical therapeutic strategies have been recently introduced, their success depends on an accurate assessment of the extension and severity of the disease.
Keywords
- Paramagnetic Contrast Agent
- Hyoscine Butylbromide
- Positive Oral Contrast
- Positive Contrast Agent
- Single Shot Sequence
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
This is a preview of subscription content, log in via an institution.
Buying options
Tax calculation will be finalised at checkout
Purchases are for personal use only
Learn about institutional subscriptionsReferences
Loftus EV Jr, Schoenfeld P, Sandborn WJ (2002) The epidemiology and natural history of Crohn’s disease in population-based patient cohorts from North America: a systematic review. Aliment Pharmacol Ther 16:51–60
Cho JH (2008) The genetics and immunopathogenesis of inflammatory bowel disease. Nat Rev Immunol 8:458–466
Gramlich T, Petras RE (2007) Pathology of inflammatory bowel disease. Semin Pediatr Surg 16:154–163
Leyendecker JR, Bloomfeld RS, DiSantis DJ, Waters GS, Mott R, Bechtold RE (2009) MR Enterography in the Management of Patients with Crohn Disease Radiographics 29:1827–1846
Furukawa A, Saotome T, Yamasaki M, Maeda K, Nitta N, Takahashi M, Tsujikawa T, Fujiyama Y, Murata K, Sakamoto T (2004) Cross-sectional Imaging in Crohn Disease Radiographics 243 689–702
Gourtsoyiannis N, Papanikolaou N, Grammatikakis J, Prassopoulos P (2002) MR enteroclysis: technical considerations and clinical applications. Eur Radiol 12:2651–2658
Low RN, Sebrechts CP, Politoske DA et al (2002) Crohn disease with endoscopic correlation: singleshot fast spin-echo and gadolinium-enhanced fatsuppressed spoiled gradient-echo MR imaging. Radiology 222:652-660
Low RN, Francis IR, Politoske et al (2000) Crohn’s disease evaluation: comparison of contrast-enhanced MR imaging and single-phase helical CT scanning. J Magn Reson Imaging 11:127–135
Kuehle CA, Ajaj W, Ladd SC, Massing S, Barkhausen J, Lauenstein TC. (2006) Hydro-MRI of the small bowel: effect of contrast volume, timing of contrast administration, and data acquisition on bowel distention. AJR Am J Roentgenol 187: W375–W385
Ajaj W, Goehde SC, Schneemann H, Ruehm SG, Debatin JF, Lauenstein TC (2004) Oral contrast agents for small bowel MRI: comparison of different additives to optimize bowel distension. Eur Radiol 14: 458–464
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Additional information
Multiple Choice Questionnaire
-
1)
Which signs are typical consequences of fibrotic involution due to the chronic inflammation of Crohn’s disease?
-
a.
homogeneously enhancing bowel wall
-
b.
enlargement of mesenteric lymph nodes
-
c.
stratified enhancement of the bowel wall with a “target” appearance and fibrofatty proliferation
-
d.
“cobblestone appearance”
-
e.
mural ulcerations
-
a.
-
2)
Which is the best sequence to rule out the presence of the “comb sign”?
-
a.
TSE T2 weighted single shot sequences
-
b.
TSE T2 weighted sequences with fat-suppression
-
c.
true FISP sequences
-
d.
GR fat-suppressed T1 weighted sequences with the intravenous administration of a paramagnetic contrast agent
-
e.
GR T1 weighted sequences with the intravenous administration of contrast agent and without fat suppression
-
a.
-
3)
Which are the main advantages of true-FISP sequences?
-
a.
very fast imaging
-
b.
GRE unspoiled sequences benefit from the residual transverse magnetization
-
c.
assessment of the residual peristaltic activity of the pathological bowel segment
-
d.
reduced motion artifacts
-
e.
all of the above
-
a.
1. c — 2.d — 3.e
Rights and permissions
Copyright information
© 2013 Springer-Verlag Italia
About this chapter
Cite this chapter
Iafrate, F., Ciolina, M., Pichi, A., Laghi, A. (2013). A 34-Year-Old Woman with Chronic Inflammation Due to Crohn’s Disease: Typical MRI Signs. In: Trecca, A. (eds) Atlas of Ileoscopy. Springer, Milano. https://doi.org/10.1007/978-88-470-5205-5_19
Download citation
DOI: https://doi.org/10.1007/978-88-470-5205-5_19
Publisher Name: Springer, Milano
Print ISBN: 978-88-470-5204-8
Online ISBN: 978-88-470-5205-5
eBook Packages: MedicineMedicine (R0)