Abstract
The gastrointestinal (GI) tract is one of the most complex organs in the body. Its ability to extract from food a chemically mixed compound, the nutrients required for normal body growth and maintenance and eliminate unnecessary or noxious substances as well as control the immunological environment attests to an amazing organizational capacity.
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References
Williamson RCN (1978) Intestinal adaptation. Structural, functional and cytokinetic changes. N Eng J Med 298:1393–1402.
Dowling RH (1982) Small bowel adaptation and its regulation. Scand J Gastroenterol 17(Suppl 174):53–74.
Bristol JB, Williamson RCN, Chir M (1988) Nutrition, operation, and intestinal adaptation. JPEN 12:299–309.
Steiner M, Bourge HR, Freeman LS, Gray SJ (1968) Effect of starvation on the tissue composition of the small intestine in rat. Am J Physiol 215:75–77.
Inoue Y, Grant JP, Snyder PJ (1993) Effect of glutamine-supplemented total parenteral nutrition on recovery of the small intestine after starvation atrophy. JPEN 17:165–170.
Sarac TP, Souba WW, Miller JH et al (1994) Starvation induces differential small bowel luminal amino acid transport. Surgery 116:679–686.
Illig KA, Ryan CK, Hardy DJ et al (1992) Total parenteral nutrition-induced changes in gut mucosal function: Atrophy alone is not the issue. Surgery 112:631–637.
Sitrin HS, Bryant M, Ellis LM (1992) Species differences in TPN-induced intestinal villus atrophy. JPEN 16:S30.
Buchman AL, Moukarzei AA, Bhuta S et al (1995) Parenteral nutrition is associated with intestinal morphology and functional changes in humans. JPEN 19:453–460.
Guedon C, Schmitz J, Lerebours E et al (1986) Decreased brush border hydrolase activities without gross morphologic changes in human intestinal mucosa after prolonged total parenteral nutrition of adults. Gastroenterology 90:373–378.
Heyland DK, Cook DJ, Guyatt GH (1993) Enterai nutrition in the critically ill patient: A critical review of the evidence. Intensive Care Med 19:435–442.
Lew JI, Rombeau JI (1993) The effects of nutrients on the intestine epithelium. In: Furst P (ed) New strategies in clinical nutrition. Zuckschwerd, Münich, pp 64–84.
Lipman TO (1995) Bacterial translocation and enteral nutrition in humans: an outsider looks in. JPEN 19:156–165.
Spitz J, Ghandi S, Hecht G, Alverdy J (1993) The effects of total parenteral nutrition on gastrointestinal function. Clin Nutr 12:S33–S37.
Deitch EA, Taylor M, Grisham M, Ma L, Bridges W, Berg R (1989) Endotoxin induces bacterial translocation and increase xanthine oxidase activity. J Trauma 29:1679–1683.
Baily RW, Bulkley GB, Levy KI, Anderson JH, Zuidema GD (1982) Pathogenesis of non-occlusive mesenteric ischaemia: studies in a porcine model induced by pericardial tamponade. Surg Forum 33:194–196.
Haglund U, Bulkley GB, Granger DN (1987) On the pathophysiology of intestinal ischemic injury. Acta Chir Scand 153:321–324.
O’Dwyer ST, Michie HR, Zigler TR et al (1988) A single dose of endotoxin increase intestinal permeability in healthy humans. Arch Surg 123:1459–1464.
Finck MP, Antonsson JB, Wang H, Rothschild HR (1991) Increased intestinal permeability in endotoxic pigs: mesenteric hypoperfusion as an etiologic factor. Arch Surg 126:211–218.
Reilly PM, Bulkley GB (1993) Vasoactive mediators and splanchnic perfusion. Crit Care Med 21:S55–S68.
Rombeau JL, Takala J (1997) Summary of round table conference: gut dysfunction in critical illness. Intensive Care Med 23:476–479.
Klein S, Alpers DH, Grand RJ, Levin MS et al (1998) Advances in nutrition and gastroenterology: Summary of the 1997 ASPEN research workshop. JPEN 22:3–13.
Cerra FB, Benitez MR, Blackburn GL, Irwin RS et al (1997) Applied nutrition in ICU patients: consensus statement of the American College of Chest Physicians. Chest 11:769–778.
Takala J (1996) Determinants of splanchnic blood flow. Br J Anaesth 77:50–58.
Ruokonen E, Uusaro A, Alhava E, Takala J (1997) The effect of dobutamine infusion on splanchnic blood flow and oxygen transport in patients with acute pancreatitis. Intensive Care Med 23:732–737.
Doglio GR, Pusajo JF, Egurrola MA, Gutierrez G et al (1991) Gastric mucosal pH as a prognostic index of mortality in critically ill patients. Crit Care Med 19:1037–1040.
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© 1999 Springer-Verlag Italia, Milano
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Zanello, M., Di Mauro, L., Santoro, C. (1999). The gut in local and systemic disease. In: Guarnieri, G., Iscra, F. (eds) Metabolism and Artificial Nutrition in the Critically Ill. Topics in Anaesthesia and Critical Care. Springer, Milano. https://doi.org/10.1007/978-88-470-2901-9_19
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DOI: https://doi.org/10.1007/978-88-470-2901-9_19
Publisher Name: Springer, Milano
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