Acute Coronary Syndrome
Term used to describe a constellation of symptoms resulting from acute myocardial ischemia.
Two major groups: (1) ST elevation myocardial infarct (STEMI) and (2) non-ST elevation myocardial infarction (NSTEMI and unstable angina).
Treatments: (1) STEMI, reperfusion therapy; (2) NSTEMI, not treated with thrombolysis.
Vasodilator agent used in myocardial stress perfusion.
Most commonly used stress agent due to its ultrashort half-life (<10 s).
Dose: 140 μg/kg/min for 3–6 min.
Caffeine or other methylxanthines should be avoided for 24 h before the administration.
Contraindications: (1) high-grade AV block; (2) asthma or COPD; (3) sinus bradycardia; (4) systemic hypotension (BP < 90 mmHg); (5) severe carotid stenosis.
Side effects: transient heart block, transient hypotension, transient tachycardia, bronchospasm.
Antagonist: aminophylline, 50–100 mg over 1 min, injection can be repeated up to 250 mg total dose.
See also “ Perfusion imaging, myocardial”.
KeywordsAortic Valve Aortic Dissection Fabry Disease Left Ventricular Assist Device Bicuspid Aortic Valve
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