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General Concepts on Radioguided Sentinel Lymph Node Biopsy: Preoperative Imaging, Intraoperative Gamma-Probe Guidance, Intraoperative Imaging, and Multimodality Imaging

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Atlas of Lymphoscintigraphy and Sentinel Node Mapping

Abstract

Lymphoscintigraphy is an essential component for radio-guided sentinel lymph node biopsy (SLNB), which is now routinely employed in clinical practice for treating patients with breast cancer [1] or melanoma [2]. SLNB is used to assess the tumoral involvement of lymph nodes not only for staging (parameter N of the TNM [tumor, node, metastases] system) and prognostic stratification, but also for therapeutic purposes [3]. This procedure is part of the so-called “radioguided surgery,” a whole spectrum of nuclear medicine applications based on the combination of preoperative imaging, intraoperative detection, and postoperative techniques, involving close collaboration between at least three different specialties (nuclear medicine, surgery, pathology, and sometimes radiology and health physics as well) [4].

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Author information

Authors and Affiliations

  1. Regional Center of Nuclear Medicine, University of Pisa Medical School, Pisa, Italy

    Federica Orsini, Federica Guidoccio & Giuliano Mariani

  2. Nuclear Medicine, Hospital Clínic Barcelona, Barcelona, Spain

    Sergi Vidal-Sicart

  3. Nuclear Medicine, Division of Diagnostic Oncology, Netherlands Cancer Institute - Antoni van Leeuwenhoek Hospital, Amsterdam, the Netherlands

    Renato A. Valdés Olmos

Authors
  1. Federica Orsini
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  2. Federica Guidoccio
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  3. Sergi Vidal-Sicart
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  4. Renato A. Valdés Olmos
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  5. Giuliano Mariani
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Corresponding author

Correspondence to Federica Orsini .

Editor information

Editors and Affiliations

  1. Regional Center of Nuclear Medicine, University of Pisa Medical School, Pisa, Italy

    Giuliano Mariani , Gianpiero Manca  & Federica Orsini ,  & 

  2. Nuclear Medicine, Hospital Clínic Barcelona, Barcelona, Spain

    Sergi Vidal-Sicart

  3. Nuclear Medicine, Division of Diagnostic Oncology, Netherlands Cancer Institute, Antoni van Leeuwenhoek Hospital, Amsterdam, the Netherlands

    Renato A. Valdés Olmos

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Orsini, F., Guidoccio, F., Vidal-Sicart, S., Valdés Olmos, R.A., Mariani, G. (2013). General Concepts on Radioguided Sentinel Lymph Node Biopsy: Preoperative Imaging, Intraoperative Gamma-Probe Guidance, Intraoperative Imaging, and Multimodality Imaging. In: Mariani, G., Manca, G., Orsini, F., Vidal-Sicart, S., Valdés Olmos, R.A. (eds) Atlas of Lymphoscintigraphy and Sentinel Node Mapping. Springer, Milano. https://doi.org/10.1007/978-88-470-2766-4_7

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  • DOI: https://doi.org/10.1007/978-88-470-2766-4_7

  • Publisher Name: Springer, Milano

  • Print ISBN: 978-88-470-2765-7

  • Online ISBN: 978-88-470-2766-4

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