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Hemorrhage, Stroke, and Ischemia of the Neonatal Brain

  • Maria I. Argyropoulou

Abstract

The pattern of neonatal brain lesions associated with hypoxia-ischemia depends not only on the severity of the event but also on gestational age at birth. The immature brain of preterm babies reacts to hypoxia-ischemia differently than does the brain of full-term babies [1, 2]. White matter lesions are mainly observed in premature babies, whereas gray matter lesions are predominant in full-term babies. Germinal matrix and intraventricular hemorrhage, parenchymal venous hemorrhagic infarction (PVHI), post-hemorrhagic hydrocephalus, and periventricular leuko-malacia (PVL) with a focal necrotic and a diffuse component represent the spectrum of lesions responsible for the encephalopathy of prematurity [2]. Parasagittal watershed infarcts, injury to the basal ganglia, and the perirolandic cortex or more extensive lesions associated with macrocystic encephalomalacia comprise the spectrum of lesions following hypoxia-ischemia in the full-term baby [3–5]. Stroke is an important cause of mortality and morbidity in the neonatal period [6, 7]. Neonatal stroke is less common than adult stroke but more common than that in childhood, and the carotid artery territory is most commonly affected [6, 7].

Keywords

Diffusion Tensor Imaging Magnetization Transfer Ratio Perinatal Asphyxia Periventricular White Matter Neonatal Brain 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag Italia 2012

Authors and Affiliations

  • Maria I. Argyropoulou
    • 1
  1. 1.Department of Radiology, Medical SchoolUniversity of IoanninaIoanninaGreece

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