The HPA Axis and the Regulation of Energy Balance
The hypothalamic-pituitary-adrenal (HPA) axis is a neuroendocrine complex comprising the hypothalamus, hypophysis, and peripheral adrenal glands, all of which are joined in a feedback-loop-generating network of neural and chemical communications. The HPA is fundamental for the regulation of basic functions such as eating, drinking, reproduction, locomotion, and response to stress, thereby assuring individual and species survival.
KeywordsBrown Adipose Tissue ACTH Secretion Zona Fasciculata Zona Reticularis Orexigenic Effect
Unable to display preview. Download preview PDF.
- 2.Frohman LA, Felig PA (eds) (2001) Endocrinology and Metabolism 4th ed.: McGrow-HillGoogle Scholar
- 12.Smith SR, de Jonge L, Pellymounter M, Nguyen T, Harris R, York D, Redmann S, Rood J, Bray GA (2001) Peripheral administration of human corticotropinin-releasing hormone: a novel method to increase energy expenditure and fat oxidation in man. J Clin Endocrinol Metab 86(5): 1991–8PubMedCrossRefGoogle Scholar