Improving Ventilation by Reaeration of Atelectatic Regions with Perfluorocarbons

  • S. Böhm
  • A. Fraterman
  • B. Lachmann
Conference paper


Patients with acute respiratory failure have a disturbed pulmonary surfactant system which causes an elevated surface tension at the air-tissue interface of the alveoli in the lung. This elevated surface tension leads to end-expiratory alveolar collapse, to atelectasis, to an increase in right-to-left shunt, and to a decrease in PaO2. Therefore, in these patients it is essential to apply a ventilatory treatment that is aimed at recruiting those collapsed alveoli and improving gas-exchange at the lowest possible airway pressures.


Acute Lung Injury Acute Respiratory Failure Conventional Mechanical Ventilation Exogenous Surfactant Partial Liquid Ventilation 
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Copyright information

© Springer-Verlag Italia 1997

Authors and Affiliations

  • S. Böhm
  • A. Fraterman
  • B. Lachmann

There are no affiliations available

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