Pain Control: From Basic Research to Clinical Application

  • M. Tiengo
Conference paper


This presentation describes first the enormous contribution of basic research (i.e., neurophysiology, neurochemistry, and neuropharmacology) to advances in algology, then the protocol, both statistical and ethical, legislated by the Italian government for the passage of molecules from development to use as pharmaceuticals, and finally, the clinical phase which tests the use of these pharmaceuticals before they can be released onto the market. Examples of basic and clinical research are provided.


Pain Stimulation Tail Flick Opiate Antagonist Placebo Analgesia Spinal Subarachnoid Space 
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© Springer-Verlag Italia 1997

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  • M. Tiengo

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