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Malignant Tumors of the Dia/metaphysis

  • Conference paper
Highlights of Pediatric Radiology

Part of the book series: Syllabus ((SYLLABUS))

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Abstract

There are two main types of skeletal malignancies in children: round cell tumors and tumors that arise from mesenchymal elements [1]. Round cell tumors infiltrate the marrow, whereas mesenchymal tumors arise in areas of active ossification of cartilage and deposition of new bone. Marrow-infiltrating tumors include metastatic neuroblastoma, Ewing sarcoma, lymphoma, and Langerhans cell histiocytosis. All round cell tumors follow the distribution of hematopoietic bone marrow and do not produce tumor matrix. They destroy bone and are thus radiographically lytic. They also, however, elicit periosteal bone deposition and reactive bone formation both of which can increase radiographic density. Tumors related to the formation of cartilage and bone include osteogenic sarcomas, and cartilaginous tumors. These tumors tend to occur in the vicinity of the fastest growing physes (distal femur, proximal tibia, proximal humerus), and produce characteristic tumor matrix.

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Author information

Authors and Affiliations

  1. Department of Radiology, Children’s Hospital and Harvard Medical School, Boston, USA

    D. Jaramillo

Authors
  1. D. Jaramillo
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Editor information

Editors and Affiliations

  1. Department of Radiology, Hadassah Medical Organization, Kiryat Hadassah, Jerusalem, Israel

    J. Bar-Ziv

  2. Department of Imaging, Schneider Children’s Medical, Center of Israel, Petah-Tikva, Israel

    G. Horev

  3. Service de Radiologie, Hôpital Sain Vincent-de-Paul, Paris, France

    G. Kalifa

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© 1999 Springer-Verlag Italia, Milano

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Jaramillo, D. (1999). Malignant Tumors of the Dia/metaphysis. In: Bar-Ziv, J., Horev, G., Kalifa, G. (eds) Highlights of Pediatric Radiology. Syllabus. Springer, Milano. https://doi.org/10.1007/978-88-470-2253-9_14

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  • DOI: https://doi.org/10.1007/978-88-470-2253-9_14

  • Publisher Name: Springer, Milano

  • Print ISBN: 978-88-470-0061-2

  • Online ISBN: 978-88-470-2253-9

  • eBook Packages: Springer Book Archive

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