Abstract
Multiple organ failure is frequently observed in critically ill patients, despite the restoration of whole-body haemodynamics. Alterations in microvascular blood flow may play a crucial role in the development of multiple organ failure in these patients. These alterations can have important implications. In rats submitted to 60 min of severe haemorrhage with subsequent restauration of blood volume, Zhao et al. [1] observed that microvascular alterations were more severe in rats that will subsequently die compared to survivors, despite similar whole-body haemodynamics.
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De Backer, D., Dubois, MJ., Creteur, J. (2002). Microcirculation in Critical Illness. In: Baue, A.E., Berlot, G., Gullo, A., Vincent, JL. (eds) Sepsis and Organ Dysfunction. Springer, Milano. https://doi.org/10.1007/978-88-470-2213-3_9
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DOI: https://doi.org/10.1007/978-88-470-2213-3_9
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