Abstract
The increasing resistance of more and more bacteria to the antibiotics originally designed to treat them has created a unique challenge for the medical profession and the pharmaceuticals industry.
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References
Kollef MH, Sherman G, Ward S, Fraser VJ (1999) Inadequate antimicrobial treatment of infections: a risk factor for hospital mortality among critically ill patients. Chest 115: 462–474
Dupont H, Mentec H, Sollet JP, Bleichner G (2001) Impact of appropriateness of initial antibiotic therapy on the outcome of ventilator associated pneumonia. Intensive Care Med 27: 355–362
Ibrahim EH, Sherman G, Ward S, et al (2000) The influence of inadequate antimicrobial treatment of bloodstream infections on patients outcome in the ICU setting. Chest 118: 146–155
Handwerger S, Raucher B, Altarac D, et al (1993) Nosocomial outbreak due to Enterococcus faecium highly resistant to vancomycin, penicillin and gentamicin. Clin Infect Dis 16: 750–755
Nosocomial enterococci resistant to vancomycin-United States, 1989–1993 (1993) MMWR 42: 597–599
Iwen PC, Kelly DM, Linder J, et al (1997) Change in prevalence and antibiotic resistance of Enterococcus species isolated from blood cultures over an 8-year period. Antimicrob Agents Chemother 41: 494–495
Murray BE (2000) Vancomycin-resistant enterococcal infections. N Engl J Med 342: 710–721
Hiramatsu K, Hanaki H, Ino T, et al (1997) Methicillin-resistant Staphylococcus aureus clinical strain with reduced vancomycin susceptibility. J Antimicrob Chemother 40: 135–136
Hiramatsu K, Aritaka N, Hanaki H, et al (1997) Dissemination in Japanese hospitals of strains of Staphylococcus aureus heterogeneously resistant to vancomycin. Lancet 350: 1670–1673
Rotun SS, McMath V, Schoonmaker DJ, et al (1999) Staphylococcus aureus with reduced susceptibility to vancomycin isolated from a patient with fatal bacteremia. Emerg Infect Dis 5: 147–149
Edmond MB, Wallace SE, McClish DK, et al (1999) Nosocomial bloodstream infections in the United States hospitals: a three-year analysis. Clin Infect Dis 29: 239–244
Vincent J-L, Bihari DJ, Suter PM, et al (1995) The prevalence of nosocomial infection in intensive care units in Europe. JAMA 274: 639–644
Fluit AC, Jones ME, Schmidt F-J, et al SENTRY Participants Group (2000) Antimicrobial susceptibility and frequency of occurrence of clinical blood isolates in Europe from the SENTRY antimicrobial surveillance program, 1997 and 1998. Clin Infect Dis 30: 454–460
Flournoy DJ, Reinert RL, Bell-Dixon C, Gentry CA (2000) Increasing antimicrobial resistance in gram-negative bacilli isolated from patients in intensive care units. Infect Control Hosp Epidemiol 28: 244–250
Wu LC, Brook JH (2000) Multiple antibiotic resistant bacteria in New Jersey hospitals, 1992–1.998 (abstract). International Conference on Emerging Infectious Diseases. Atlanta, Georgia, USA, July 16–19, 2000. Centers for Disease Control and Prevention, Georgia, p 75
Centers for Disease Control and Prevention (2000) Laboratory capacity to detect antimicrobial resistance, 1998. MMWR Morb Mortal Wkly Report 48: 1167–1171
Garner JS, Hospital Infection Control Practices Advisory Committee (1996) Guideline for isolation precautions in hospitals. I. Evolution of isolation practices. Am J Infect Control 24: 24–31
Larson EL, APIC Guidelines Committee (1995) APIC guideline for handwashing and hand antisepsis in health care settings. Am J Infect Control 23: 251–269
Hospital Infection Control Practice Advisory Committee (HICPAC) (1995) Recommendations for preventing the spread of vancomycin resistance. Infect Control Hosp Epidemiol 16: 105–113
Quale J, Landman D, Atwood E, et al (1996) Experience with a hospital-wide outbreak of vancomycin-resistant enterococci. Am J Infect Control 24: 372–379
Moulin F, Dumontier S, Saulnier P (1996) Surveillance of intestinal colonization and of infection by vancomycin-resistant enterococci in hospitalized cancer patients. Clin Microbiol Infect 34: 751–752
Bradley SJ, Wilson ALT, Allen MC, et al (1999) The control of hyperendemic glycopeptide-resistant Enterococcus spp. on a haematology unit by changing antibiotic usage. J Antimicrob Chemother 43: 261–266
Wenzel RP, Reagan DR, Bertino JS, et al (1998) Methicillin-resistant Staphylococcus aureus outbreak: a consensus panel’s definition and management guidelines. Am J Infect Control 26: 102–110
CDC interim guidelines for prevention and control of staphylococcal infections associated with reduced susceptibility to vancomycin. (2000) MMWR 48: 1167–1171
James JK, Palmer SM, Levine DP, Rybak MJ (1999) Comparison of conventional dosing versus continuous infusion vancomycin therapy for patients with suspected or documented Gram positive infections. Antimicrob Agents Chemother 40: 696–700
Climo M, Patron RL, Archer G (1999) Combinations of vancomycin and beta-lactams are synergistic in the treatment of vancomycin intermediate susceptible S.aureus Antimicrob Agents Chemother 43 (7): 1747–1753
Cercenado E, Eliopoulos GM, Wennerstern CB, Moellering RC Jr. (1992) Absence of synergistic activity between ampicillin and vancomycin against highly vancomycin-resistant enterococci. Antimicrob Agents Chemother 36: 2201–2203
Fridkin SK, Welbel SF, Weinstein RA (1996) Magnitude and prevention of nosocomial infections in the intensive care unit. Infect Dis Clin North Am 11: 479–496
Rice LB, Eckstein EC, DeVente J, et al (1996) Ceftazidime-resistant Klebsiella pneumoniae isolates recovered at the Cleveland Department of Veterans Affairs Medical Center. Clin Infect Dis 23: 118–124
Karas JA, Pillay DG, Muckart D, et al (1996) Treatment failure due to extended spectrum (3-lactamase. J Antimicrob Chemother 37: 203
Jacoby GA, Han P. (1996) Detection of extended-spectrum 3-lactamases in clinical isolates of Klebsiella pneumoniae and Escherichia coli. J Clin Microbiol 34: 908–911
Burwen DR, Banerjee SN, Gaynes RP, et al (1994) Ceftazidime resistance among selected nosocomial gram-negative bacilli in the United States, J Infect Dis 170: 1622–1625
Piroth L, Aube H, Doise J, et al (1998) Spread of extended-spectrum-lactamase—producing Klebsiella pneumoniae: are (3-lactamase inhibitors of therapeutic value? Clin Infect Dis 27: 76–80
Schiappa DA, Hayden MK, Matushek MG, et al (1996) Ceftazidime-resistant Klebsiella pneumoniae and Escherichia coli bloodstream infection: a case-control and molecular epidemiologic investigation. J Infect Dis 174: 529–536
Monnet D, Biddle JW, Edwards JR, et al (1997) Evidence of interhospital transmission of extended-spectrum-lactam—resistant Klebisella pneumoniae in the United States, 1986–1993. Infect Control Hosp Epidemiol 18: 492–498
Rex JH, Pfaller MA, Rinaldi MG, et al (1993) Antifungal susceptibility testing. Clin Microbiol Rev 6: 367–381
McCaig LF, Hughes JM (1995) Trends in antimicrobial drug prescribing among office-based physicians in the United States. JAMA 273: 214–219
Johnson EM, Warnock DW, Luker J, et al (1995) Emergence of azole drug resistance in Candida species from HIV-infected patients receiving prolonged fluconazole therapy for oral candidosis. J Antimicrob Chemother 35:103–114 -°
Maenza JR, Keruly JC, Moore RD, et al (1996) Risk factors for fluconazole-resistant candidiasis in human immunodeficiencyvirus-infected patients. J Infect Dis 173: 219–225
Abi-Said D, Anaissie E, Uzon O, et al (1997) The epidemiology of hematogenous candidiasis caused by different Candida species. Clin Infect Dis 24: 1122–1128
Fridkin SK, Jarvis WR (1996) Epidemiology of nosocomial fungal infections. Clin Microbiol Rev 9: 499–511
Pfaller MA, Jones RN, Messer SA, et al (1998) National surveillance of nosocomial blood stream infection due to Candida albicans: frequency of occurrence and antifungal susceptibility in the SCOPE Program. Diagn Microbiol Infect Dis 31: 327–332
World Health Organization. (2000) Overcoming Antimicrobial Resistance - World Health Report on Infectious Diseases 2000. Available at http://www.who.int/infectious-disease-report/2000/index.html. World Health Organization, Geneva
Interagency Task Force on Antimicrobial Resistance (2000) Draft public health action plan to combat antimicrobial resistance. I Domestic issues. Available at website: http://www.cdc.gov/drugresistance/actionplan/index.htm Atlanta. Centers for Disease Control and Prevention
Association for the Prudent Use of Antibiotics. (2000) Response to the Draft Public Health Action Plan on Antimicrobial Resistance. Available at APUA website: http://www.healthsci.tufts.edu/apua/apua.html
Goldmann DA, Weinstein RA, Wenzel RP, et al (1996) Strategies to prevent and control the emergence and spread of antimicrobial-resistant microorganisms in hospitals. JAMA 275: 234–240
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Grossi, P. (2002). Empirical Antibiotic Treatment in ICU Patients. In: Baue, A.E., Berlot, G., Gullo, A., Vincent, JL. (eds) Sepsis and Organ Dysfunction. Springer, Milano. https://doi.org/10.1007/978-88-470-2213-3_11
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DOI: https://doi.org/10.1007/978-88-470-2213-3_11
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