Abstract
Functional magnetic resonance imaging (fMRI), which uses BOLD (blood oxygenation level dependent contrast) technique, allows the identification of physiologically activated brain areas by means of a local and transient magnetic resonance (MR) signal increase [l]. The physical and physiological bases of the observed signal changes are not totally understood. The most accepted theory associates a local decrease in deoxyhemoglobin concentration within the venous microcirculation with the MR signal increase detected during brain activation [2].
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Kwong KK, Belliveau JW, Chesier DA et al (1992) Dynamic magnetic resonance imaging of human brain activity during primary sensory stimulation. Proc Natl Acad Sci USA 89: 5675–5679
Ogawa S, Tank D, Menon R, Ellermann J, Kim S, Markle H, Ugurbil K (1992) Intrinsic signal changes accompanying sensory stimulation: functional brain mapping with magnetic resonance imaging. Proc Natl Acad Sci USA 89: 5951–5955
Rao S, Binder JR, Bandettini BS et al (1993) Functional magnetic resonance imaging of complex human movements. Neurology 43: 2311–2318
Tyszka J, Grafton S, Chew W, Woods R, Colletti P (1994) Parceling of mesial frontal motor areas during ideation and movement using functional magnetic resonance imaging at 1.5 Tesla. Ann Neurol 35: 746–749
Daniels DL, Yetkin ZF, Mark LP, Naughton VM (1994) Comparison of Functional MR Imaging and Anatomic Methods for Locating the Sensorymotor Cortex. Radiology 193: 186
Yousry T, Schmid U, Jassoy A et al (1995) Topography of the cortical motor hand area: prospective study with functional MR imaging and direct motor mapping at surgery. Radiology 195: 23–29
Jack C, Thompson RM, Butts RK et al (1994) Sensory motor cortex: correlation of presurgical mapping with functional MR imaging and invasive cortical mapping. Radiology 190: 85–92
Howard R, Alsop D, Detre J, Listerud J et al (1994) Functional MRI of Regional Brain Activity in Patients with Intracerebral Gliomas and AVMs prior to Surgical or Endovascular Therapy. [Abstract] Society of Magnetic Resonance 2nd meeting, August, 701
Frahm J, Merboldt K, Haenicke W, Kleinschmidt A, Boecker H (1994) Brain or vein-oxygenation or flow? On signal physiology in functional MRI of human brain activation. NMR Biomed 7: 45–53
Righini A, Pierpaoli C, Barnett AS, Waks E, Alger JR (1995) Blue blood or black blood: R, effects in gradient echo echo planar functional neuroimaging. Magn Reson Imag 13: 369–378
Constable R, McCarthy G, Allison T, Anderson A, Gore J (1993) Functional brain imaging at 1.5 T using conventional gradient echo MR imaging techniques. Magn Reson Imag 11: 451–459
Edelman R, Siewert B, Darby D, Thangaraj V, Nobre A, Mesulam M, Warach S (1994) Qualitative mapping of cere-bral blood flow and functional localization with echo planar MR imaging and signal targeting with alternating radio-frequency. Radiology 192: 513–520
Duyn J, Mattay V, Sexton R, Sobering G, Barrios F, Liu G, Frank J, Weinberger D, Moonen C (1994) 3-Dimensional functional imaging of human brain using echo-shifted FLASH MRI. Magn Reson Med 32: 150–155
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1996 Springer-Verlag Italia, Milano
About this paper
Cite this paper
Righini, A. et al. (1996). Localization of Primary Motor Cortex in Patients with Frontal-parietal Neoplasms: an fMRI Study. In: Pavone, P., Rossi, P. (eds) Functional MRI. Syllabus. Springer, Milano. https://doi.org/10.1007/978-88-470-2194-5_23
Download citation
DOI: https://doi.org/10.1007/978-88-470-2194-5_23
Publisher Name: Springer, Milano
Print ISBN: 978-3-540-75025-3
Online ISBN: 978-88-470-2194-5
eBook Packages: Springer Book Archive