Diarrhea and malabsorption: the role of enteroscopy

  • M. Pennazio
  • F. P. Rossini


Mucosal biopsy is considered the gold standard for the diagnosis of many diseases affecting the small bowel, especially those associated with malabsorption. Diseases such as celiac sprue, Whipple’s disease, and abetalipoproteinemia, which affect the small bowel diffusely, are readily diagnosed by biopsy of the small bowel. In taking jejunal biopsies, a suction capsule has been widely used; however, endoscopic duodenal biopsies are now most commonly used in investigating small-bowel histology. Endoscopic specimens are well recognized as being equally adequate as suction-capsule biopsies in the diagnosis of villous atrophy. Nevertheless, intepretation of proximal duodenal biopsy specimens in small bowel disease may be hampered by the normal occurrence of flattened villi and Brunner’s glands and by duodenitis, often present but usually irrelevant to any malabsorption process.


Small Bowel Celiac Disease Villous Atrophy Duodenal Biopsy Small Bowel Disease 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Suggested reading

  1. Barkin JS, Schonfeld W, Thomsen S, Manten HD, Rogers AI (1985) Enteroscopy and small bowel biopsy — an improved technique for the diagnosis of small bowel disease. Gastrontest Endosc 31:215–217CrossRefGoogle Scholar
  2. Maurino E, Capizzano H, Niveloni S, Kogan Z, Valero J, Boerr L, Bai JC (1993) Value of endoscopic markers in celiac disease. Dig Dis Sci 38 2028–2033PubMedCrossRefGoogle Scholar
  3. Pennazio M, Arrigoni A, Rossini FP (1996) Push enteroscopy for evaluating patients with diarrhoea or malabsorption. Acta Endose 26:249–254CrossRefGoogle Scholar

Copyright information

© Springer-Verlag Italia, Milano 1998

Authors and Affiliations

  • M. Pennazio
  • F. P. Rossini

There are no affiliations available

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