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Standardisation, Optimisation and Organisation of Magnetic Resonance Imaging for Monitoring Clinical Trials

  • Conference paper
Book cover Magnetic Resonance Techniques in Clinical Trials in Multiple Sclerosis

Part of the book series: Topics in Neuroscience ((TOPNEURO))

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Abstract

The use of magnetic resonance imaging (MRI) in clinical trials for multiple sclerosis (MS) was pioneered by Paty et al. [1] at the University of British Columbia, Canada, following studies of the correlation of the MRI appearance of demyelinating lesions with both animal models and postmortem material [2, 3]. Without this ground-breaking work, much of the testing of new therapeutic agents seen today would be severely retarded, with much longer assessment periods, and a much more difficult pathway of the drug from laboratory to market.

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Author information

Authors and Affiliations

  1. Division of Medical Physics, University of Leicester, Leicester Royal Infirmary, Leicester, UK

    M. A. Horsfield

Authors
  1. M. A. Horsfield
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Editor information

Editors and Affiliations

  1. Neuroimaging Research Unit, Department of Neuroscience Scientific Institute Ospedale San Raffaele, University of Milan, Italy

    Massimo Filippi

  2. Department of Radiology, University of Pennsylvania, Philadelphia, USA

    Robert I. Grossman

  3. Clinical Trials Unit, Department of Neuroscience, Scientific Institute Ospedale San Raffaele, University of Milan, Italy

    Giancarlo Comi

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© 1999 Springer-Verlag Italia

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Horsfield, M.A. (1999). Standardisation, Optimisation and Organisation of Magnetic Resonance Imaging for Monitoring Clinical Trials. In: Filippi, M., Grossman, R.I., Comi, G. (eds) Magnetic Resonance Techniques in Clinical Trials in Multiple Sclerosis. Topics in Neuroscience. Springer, Milano. https://doi.org/10.1007/978-88-470-2153-2_10

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  • DOI: https://doi.org/10.1007/978-88-470-2153-2_10

  • Publisher Name: Springer, Milano

  • Print ISBN: 978-88-470-2180-8

  • Online ISBN: 978-88-470-2153-2

  • eBook Packages: Springer Book Archive

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