Is Mortality the Only Outcome Measure in ICU Patients?
Clinical trials, by definition, need to have an aim, an outcome measure. Indeed, there is no point conducting a trial if there is no endpoint in view. The choice of the outcome measure employed will vary according to the agent/technique being assessed but in intensive care medicine, the majority of clinical trials currently focus on the 28 day all-cause mortality rate. This measure may, however, not necessarily be the most appropriate, and we will discuss the reasons for this, and possible alternatives, in this paper.
KeywordsOrgan Failure Sequential Organ Failure Assessment Infection Type Intensive Care Medicine Veteran Administration
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