Problema: malattie prostatiche (infezione, ipertrofia benigna e cancro della prostata)

  • S. Alan McNeill
  • Steve Ken Wing Leung
  • M. C. Bishop


L’ipertrofia benigna della prostata (Benign Prostatic Hyperplasia, BPH) e il cancro della prostata sono due malattie distinte che comunemente colpiscono la prostata degli uomini nella fase dell’invecchiamento. La prostata è una ghiandola sessuale accessoria, situata intorno all’uretra alla base della vescica, le cui dimensioni aumentano dopo la pubertà sotto l’influenza del testosterone. I tessuti ghiandolari della prostata sono organizzati in tre zone, come descritto da McNeal (1981,1988). Queste affezioni hanno la tendenza a colpire parti differenti della ghiandola. La BPH colpisce quasi esclusivamente la zona di transizione della prostata che circonda l’uretra. Benché possa anche sopraggiungere nelle zone centrali e di transizione, il cancro della prostata interessa il più delle volte la zona periferica della ghiandola, ragione per la quale l’esplorazione rettale (Digital Rectal Examination, DRE) è molto utile alla valutazione della prostata. Poiché queste malattie colpiscono di preferenza regioni distinte, non sorprende che la BPH tenda a presentarsi con sintomi legati all’ostruzione urinaria più precocemente del cancro della prostata, mentre i pazienti che presentano sintomi di ostruzione urinaria per cancro della prostata saranno spesso a uno stadio avanzato della malattia (Fig. 1.9.1).
Fig. I.9.1.

Anatomia regionale della prostata


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Copyright information

© Springer-Verlag Italia 2010

Authors and Affiliations

  • S. Alan McNeill
    • 1
  • Steve Ken Wing Leung
    • 2
  • M. C. Bishop
    • 3
  1. 1.Department of UrologyWestern General HospitalEdinburghUK
  2. 2.Prostate Research Group, School of Molecular and Clinical MedicineThe University of Edinburgh, Western General HospitalEdinburghUK
  3. 3.Department of UrologyNottingham City Hospital NHS TrustNottinghamUK

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