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Fetal infections: Rubella, HIV, HCV, HBV, and Human Parvovirus B19

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Neonatology

Abstract

Rubella: Salient Points

  • Congenital rubella (CR) infection leads to damage in over 80% of fetuses during the first trimester of pregnancy, in 25–34% of cases in the second trimester, while no malformations occur in the third trimester.

  • CR syndrome (CRS) is characterized by the combination of cardiac, ocular, and hearing defects, although any organ may be affected leading to long-term disabilities.

  • To prevent CRS it is essential to verify before or during pregnancy, that all women have natural or vaccine-induced immunity to the rubella virus.

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Tovo, PA., Bezzio, S., Gabiano, C. (2012). Fetal infections: Rubella, HIV, HCV, HBV, and Human Parvovirus B19. In: Buonocore, G., Bracci, R., Weindling, M. (eds) Neonatology. Springer, Milano. https://doi.org/10.1007/978-88-470-1405-3_113

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  • DOI: https://doi.org/10.1007/978-88-470-1405-3_113

  • Publisher Name: Springer, Milano

  • Print ISBN: 978-88-470-1404-6

  • Online ISBN: 978-88-470-1405-3

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