Abstract
Familial adenomatous polyposis is a severe autosomal dominant disease with complex clinical symptoms and a high risk of colorectal and other cancers. Genetic counseling and testing is recommended and is important for probands but also for other relatives at risk. A germline mutation in the APC gene is the cause of the disease in most families. Genetic counseling is a process that includes several sessions with the patient and family members, and should help the family in process of making decisions about testing and cancer prevention. The primary and secondary prevention is complex and should be provided by several professionals with in-depth knowledge of the syndrome. Many psychological and social problems may be anticipated and should not be overlooked.
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Foretová, L., Skřička, T.š. (2009). Psychological and Medico-Legal Aspect of Genetic Counseling in Familial Adenomatous Polyposis. In: Delaini, G.G., Skřička, T., Colucci, G. (eds) Intestinal Polyps and Polyposis. Springer, Milano. https://doi.org/10.1007/978-88-470-1124-3_21
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DOI: https://doi.org/10.1007/978-88-470-1124-3_21
Publisher Name: Springer, Milano
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