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Idrope fetale non immunologica

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Medicina dell’età prenatale

Estratto

Per molti anni gli ostetrici hanno notato la presenza di edema generalizzato dei tessuti molli in neonati che più frequentemente andavano incontro a morte [1]. John William Ballantyne, un ginecologo inglese, nel 1892 descrisse una triade costituita da edema materno, idrope fetale e placentomegalia, ma solo mezzo secolo dopo (1943) pubblicò un articolo [2] in cui veniva riconosciuto un gruppo di feti caratterizzato da uno stato anasarcatico (Fig. 19.1) in assenza di malattia emolitica del neonato: fu così descritta e codificata per la prima volta l’idrope fetale non immunologica (NIHF), definita in questo modo proprio per sottolineare l’assenza, in questa patologia, di anticorpi circolanti materni contro antigeni eritrocitari fetali.

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Bibliografia

  1. Rodriguez MM, Bruce JH, Jimenez XF et al (2005) Nonimmune hydrops fetalis in the liveborn: series of 32 autopsies. Pediatr Develop Path 8:369–378

    Article  Google Scholar 

  2. Potter EL (1943) Universal edema of the fetus unassociated with erythroblastosis. Am J Obstet Gynecol 46:130

    Google Scholar 

  3. Di Meglio A, Zuccarelli B, Albano G. Idrope fetale. www.dimed.com

    Google Scholar 

  4. Grannun PAT, Copel JA, Moya FR (1988) The reversal of hydrops fetales by intravascular intrauterine transfusion in severe isoimmune fetal anemia. Am J Obstet Gynecol 158:914–919

    Google Scholar 

  5. Iskaros J, Jauniaux E, Rodeck C (1997) Outcome of non immune hydrops fetalis diagnosed during the first half of pregnancy. Obstet Gynecol 90:321–325

    Article  PubMed  CAS  Google Scholar 

  6. Heinonen S, Ryynanen M, Kirkinen P (2000) Etiology and outcome of second trimester non-immunologic fetal hydrops. Acta Obstet Gynecol Scand 79:15–18

    Article  PubMed  CAS  Google Scholar 

  7. de Rosa G, Catalano D, Dell’Isola A (1997) Changes in fetal karyotype in non-immune hydropsfetalis. Minerva Ginecol 49:535–539

    PubMed  Google Scholar 

  8. Landrum BG, Johnson DE, Ferrara B et al (1986) Hydrops fetalis and chromosomal trisomies. Am J Obstet Gynecol 154:1114–1115

    PubMed  CAS  Google Scholar 

  9. Smrcek JM, Baschat AA, Germer U et al (2001) Fetal hydrops and hepatosplenomegaly in the second half of pregnancy: a sign of myeloproliferative disorder in fetuses with trisomy 21. Ultrasound Obstet Gynecol 17:403–409

    Article  PubMed  CAS  Google Scholar 

  10. Machin GA (1989) Hydrops revisited: literature review of 1,414 cases published in the 1980s. Am J Med Genet 34:366–390

    Article  PubMed  CAS  Google Scholar 

  11. Ruiz Villaespesa A, Suarez Mier MP, Lopez Ferrer P et al (1990) Non immunologic hydrops fetalis: An etiopathogenetic approach through the postmortem study of 59 patients. Am J Med Genet 35:274–279

    Article  PubMed  CAS  Google Scholar 

  12. Tongsong T, Chanprapaph P, Khunamornpong S, Sirichotiyakul S (2005) Sonographic features of Ebstein anomaly associated with hydrops fetalis: a report of two cases. J Clin Ultrasound 33:149–153

    Article  PubMed  Google Scholar 

  13. Holley DG, Martin GR, Brenner JI et al (1995) Diagnosis and management of fetal cardiac tumors: A multicenter experience and review of published reports. J Am Coll Cardiol 26:516–520

    Article  PubMed  CAS  Google Scholar 

  14. Nakata M, Fujiwara M, Ishikawa Y et al (2005) Prenatal diagnosis and management for a large fetal cardiac tumor complicated with hydrops fetalis. J Obstet Gynaecol Res 31:476–479

    Article  PubMed  Google Scholar 

  15. Geipel A, Krapp M, Germer U et al (2001) Perinatal diagnosis of cardiac tumors. Ultrasound Obstet Gynecol 17:17–21

    Article  PubMed  CAS  Google Scholar 

  16. O’Malley A, Barry-Kinsella C, Hughes C et al (2003) Parvovirus infects cardiac myocytes in hydrops fetalis. Pediatr Dev Pathol 6:414–420

    Article  PubMed  Google Scholar 

  17. Ferrer PL (1998) Fetal cardiac arrhythmias. In: Deal BJ, Wolff GS, Gelband H (eds) Current concepts in diagnosis and management of arrhythmias in infants and children. Futura Publishing Company, Philadelphia, pp 17–63

    Google Scholar 

  18. Kleinman CS, Nehgme RA (2004) Cardiac arrhythmias in the human fetus. Pediatr Cardiol 25:234–251

    Article  PubMed  CAS  Google Scholar 

  19. Joshi DD, Nickerson HJ, McManus MJ (2004) Hydrops fetalis caused by homozygous alpha-thalassemia and Rh antigen alloimmunization: report of a survivor and literature review. Clin Med Res 2:228–232

    Article  PubMed  Google Scholar 

  20. Winichagoon P, Sithongdee S, Kanokpongsakdi S et al (2005) Noninvasive prenatal diagnosis for hemoglobin Bart’s hydrops fetalis. Int J Hematol 81:396–399

    Article  PubMed  CAS  Google Scholar 

  21. Fesslova V, Villa L, Nava S et al (1998) Fetal and neonatal echocardiographic findings in twin-twin transfusion syndrome. Am J Obstet Gynecol 179:1056–1062

    Article  PubMed  CAS  Google Scholar 

  22. Roberts D, Neilson JP, Weindling AM (2001) Interventions for the treatment of twin-twin transfusion syndrome. Cochrane Database Syst Rev (1):CD002073

    Google Scholar 

  23. Sampath V, Narendran V, Donovan EF et al (2005) Nonimmune hydrops fetalis and fulminant fatal disease due to congenital cytomegalovirus infection in a premature infant. J Perinatol 25:608–611

    Article  PubMed  Google Scholar 

  24. Levine Z, Sherer DM, Jacobs A, Rotenberg O (1998) Nonimmune hydrops fetalis due to congenital syphilis associated with negative intrapartum maternal serology screening. Am J Perinatol 15:233–236

    PubMed  CAS  Google Scholar 

  25. Zornes SL, Anderson PG, Lott RL (1988) Congenital toxoplasmosis in an infant with hydrops fetalis. South Med J 81:391–393

    PubMed  CAS  Google Scholar 

  26. Schroter B, Chaoui R, Meisel H, Bollmann R (1999) Maternal hepatitis B infection as the cause of nonimmunologic hydrops fetalis. Z Geburtshilfe Neonatol 203:36–38

    PubMed  CAS  Google Scholar 

  27. Tsao K, Albanese CT, Harrison MR (2003) Prenatal therapy for thoracic and mediastinal lesions. World J Surg 27:77–83

    Article  PubMed  Google Scholar 

  28. Adzick NS, Flake AW, Crombleholme TM (2003) Management of congenital lung lesions. Semin Pediatr Surg 12:10–16

    Article  PubMed  Google Scholar 

  29. Laberge JM, Flageole H, Pugash D et al (2001) Outcome of the prenatally diagnosed congenital cystic adenomatoid lung malformation: a Canadian experience. Fetal Diagn Ther 16:178–186

    Article  PubMed  CAS  Google Scholar 

  30. Cha I, Adzick NS, Harrison MR et al (1997) Fetal congenital cystic adenomatoid malformations of the lung: a clinicopathologic study of eleven cases. Am J Surg Pathol 21:537–544

    Article  PubMed  CAS  Google Scholar 

  31. Stocker JT, Madewell JE, Drake RM (1977) Congenital cystic adenomatoid malformation of the lung: classification and morphologic spectrum. Hum Pathol 8:155–171

    Article  PubMed  CAS  Google Scholar 

  32. Adzick NS, Kitano Y (2003) Fetal surgery for lung lesions, congenital diaphragmatic hernia, and sacrococcygeal teratoma. Semin Pediatr Surg 12:154–167

    Article  PubMed  Google Scholar 

  33. Cass DL, Yang EY, Liechty KW et al (1997) Increased cell proliferation and decreased apoptosis in congenital cystic adenomatoid malformation: insights into pathogenesis. Surg Forum 47:659–661

    Google Scholar 

  34. Tsao K, Hawgood S, Vu L et al (2003) Resolution of hydrops fetalis in congenital cystic adenomatoid malformation after prenatal steroid therapy. J Pediatr Surg 38:508–510

    Article  PubMed  Google Scholar 

  35. Asabe K, Oka Y, Shirakusa T (2005) Fetal case of congenital cystic adenomatoid malformation of the lung: fetal therapy and a review of the published reports in Japan. Congenit Anom (Kyoto) 45:96–101

    Article  Google Scholar 

  36. Mackenzie TC, Guttenberg ME, Nisenbaum HL et al (2001) A fetal lung lesion consisting of bronchogenic cyst, bronchopulmonary sequestration, and congenital cystic adenomatoid malformation: the missing link? Fetal Diagn Ther 16:193–195

    Article  PubMed  CAS  Google Scholar 

  37. Machin GA (1997) Hydrops, cystic hygroma, hydrothorax, pericardial effusions and fetal ascites. In: Gilbert-Barness E (ed) Pathology of the fetus and infant. Mosby, St Louis, pp 163–181

    Google Scholar 

  38. Aubard Y, Derouineau I, Aubard V et al (1998) Primary fetal hydrothorax: a literature review and proposed antenatal clinical strategy. Fetal Diagn Ther 13:325–333

    Article  PubMed  CAS  Google Scholar 

  39. Burin MG, Scholz AP, Gus R et al (2004) Investigation of lysosomal storage diseases in nonimmune hydrops fetalis. Prenat Diagn 24:653–657

    Article  PubMed  Google Scholar 

  40. Anandakumar C, Biswas A, Wong YC et al (1996) Management of non-immune hydrops: 8 years’ experience. Ultrasound Obstet Gynecol 8:196–200

    Article  PubMed  CAS  Google Scholar 

  41. Mari G, Detti L, Oz U et al (2001) Accurate prediction of fetal hemoglobin by Doppler ultrasonography: a preliminary study. Am J Obstet Gynecol 184:S26

    Google Scholar 

  42. Mari G, Zimmermann R, Moise KJ Jr, Deter RL (2005) Correlation between middle cerebral artery peak systolic velocity and fetal hemoglobin after 2 previous intrauterine transfusions. Am J Obstet Gynecol 193:1117–1120

    Article  PubMed  Google Scholar 

  43. Rose CH, Bofill JA, Le M, Martin RW (2005) Non-immune hydrops fetalis: prenatal diagnosis and perinatal outcomes. J Miss State Med Assoc 46:99–102

    PubMed  Google Scholar 

  44. Santolaya J, Alley D, Jaffe R, Warsof SL (1992) Antenatal classification of hydrops fetalis. Obstet Gynecol 79:256–259

    PubMed  CAS  Google Scholar 

  45. Sohan K, Carroll SG, De La Fuente S et al (2001) Analysis of outcome in hydrops fetalis in relation to gestational age at diagnosis, cause and treatment. Acta Obstet Gynecol Scand 80:726–730

    Article  PubMed  CAS  Google Scholar 

  46. Jauniaux E (1997) Diagnosis and management of early non-immune hydrops fetalis. Prenat Diagn 17:1261–1268

    Article  PubMed  CAS  Google Scholar 

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Pietrolucci, M.E., Brienza, L., Arduini, D. (2008). Idrope fetale non immunologica. In: Medicina dell’età prenatale. Springer, Milano. https://doi.org/10.1007/978-88-470-0688-1_19

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  • DOI: https://doi.org/10.1007/978-88-470-0688-1_19

  • Publisher Name: Springer, Milano

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