Deployment of New Carbon Nanostructure: Graphene for Drug Delivery and Biomedical Applications
Graphene, the well awarded and popularly known as 2D carbon allotrope, is a versatile material. Its unique physico-chemical properties finds its application in a wide range of areas ranging from quantum physics, nanoelectronics, energy research, catalysis and engineering of nanocomposites, biomaterials and drug delivery.In principle, it is possible to produce graphene from high purity graphite sheet. Since graphite is stacked layers of many graphene sheets, bonded together by week van der Waals force and if these forces are disrupted individual graphene sheets can be separated out. In the present chapter we will discuss different methods of the synthesis of graphene like LPCVD, CVD (Chemical Vapor Deposition), thermal exfoliation, arc discharge, electrochemical exfoliation and chemical reduction. Since graphene having an innate property of hydrophobicity have the tendency to agglomeration and insolubility. To overcome the aforementioned insolubility some functionality needs to be attached to the graphene sheet. Therefore, different methods of functionalization like covalent and non-covalent approaches are also discussed. The last part of the chapter will deal with the application of graphene particularly in the drug delivery and biomedical field.
KeywordsGraphene Exfoliation Functionalization Application Drug delivery
Authors are grateful to Nano Science and Technology Initiative, Department of Science and Technology (DST), India for financial support. Authors also thank Prof. C.N.R. Rao, Prof. Shyam Sunder, Prof. A.M. Kayastha and all the lab members who are engaged and contributed directly and indirectly in the nanoscience research. Authors gratefully acknowledge the financial support from CSIR, and MNRE, New Delhi. One of the co-author M.T thanks WOS-A fellowship for the support.
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