Hierarchically Fabrication of Amylosic Supramolecular Nanocomposites by Means of Inclusion Complexation in Phosphorylase-Catalyzed Enzymatic Polymerization Field

  • J KadokawaEmail author
Part of the Advanced Structured Materials book series (STRUCTMAT, volume 75)


This chapter reviews hierarchically fabrication of eco-friendly supramolecular nanocomposites by means of inclusion complexation by amylose in phosphorylase-catalyzed enzymatic polymerization field. Amylose is a well-known polysaccharide and forms inclusion nanocomplex with various hydrophobic small molecules. A pure amylose is produced by the enzymatic polymerization using α-d-glucose 1-phosphate as a monomer and maltooligosaccharide as a primer catalyzed by phosphorylase. The author has found that a propagating chain of amylose in the enzymatic polymerization twines around hydrophobic polymers present in the reaction system to form inclusion nanocomplexes. The author named this polymerization system as ‘vine-twining polymerization’ because it is similar as the way that vine of plant grows twining around a rod. Amylosic supramolecular nanocomposite materials such as hydrogel and film were hierarchically fabricated by means of the vine-twining polymerization approach in the presence of copolymers covalently grafting with hydrophobic guest polymers. The enzymatically produced amyloses induced complexation with guest polymers in intermolecular graft copolymers, which acted as cross-linking points to form a supramolecular nanocomposite hydrogel. By using a film-formable main-chain in the graft copolymer, a supramolecular nanocomposite film was also obtained through hydrogelation. A supramolecular polymeric nanocomposite was successfully fabricated by the vine-twining polymerization using a primer-guest conjugate. The product in the vine-twining polymerization system formed a polymeric continuum of an inclusion nanocomplex, where the enzymatically produced amylose chain elongated from the conjugate included the guest segment in the other conjugate.


Amylose Supramolecule Nanocomplex Enzymatic polymerization Inclusion 


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Copyright information

© Springer India 2015

Authors and Affiliations

  1. 1.Graduate School of Science and EngineeringKagoshima UniversityKagoshimaJapan

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