Frequent Behavioural Questions with an HPV-Positive Malignancy of the Head and Neck

  • Gypsyamber D’SouzaEmail author
  • Anne M. Griffioen
  • Carole Fakhry
Part of the Head and Neck Cancer Clinics book series (HNCC)


An initial diagnosis of a head and neck malignancy is sometimes followed by a sense of relief when it becomes known that the malignancy is human papillomavirus (HPV)-positive. This is because HPV-positive malignancy is associated with improved prognosis. However, patients and their partners often wrestle with complex social and behavioural questions. Unfortunately, the answers to many of these questions have not been examined to date. At best, the most appropriate response is to say, ‘We do not know; however, initial evidence suggests that …’, with the caveat that our knowledge of oral HPV infection can only be extrapolated from related research on anogenital HPV infection. Because these cancers have implications for past, present and future relationships between patients and their partners, it is essential that any advice given to patients must be considered carefully.


Genital Contact Cervical Cancer Screening Guideline Frequent Behavioural Question Oral Exfoliate Cell 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Carole Fakhry, Gypsyamber D’Souza, Rehan Kazi and Raghav C. Dwivedi  2015

Authors and Affiliations

  • Gypsyamber D’Souza
    • 1
    Email author
  • Anne M. Griffioen
    • 2
  • Carole Fakhry
    • 3
  1. 1.Department of EpidemiologyJohns Hopkins Bloomberg School of Public HealthBaltimoreUSA
  2. 2.Department of EpidemiologyUniversity of Minnesota Medical SchoolDuluthUSA
  3. 3.Department of Otolaryngology-Head and Neck SurgeryThe Johns Hopkins University School of MedicineBaltimoreUSA

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