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Systems Biology: A New Frontier in Science

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Plant Biology and Biotechnology

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Abstract

Systems biology is an emerging field with the potential of making significant contribution to human life and other living organisms. It helps to understand the entirety of life and elucidates basic principles behind the biological life. It captures the complexity of complex biological system and explains the relationship between every gene, transcript, protein, and phenotype. Advancements in functional and structural genomics have enabled the molecular biologists to come a long way toward understanding molecular constituents of the cell. Yet, we fail to understand how organisms function. To date, we face lot of problems in complete understating of several diseases caused to plants, animals, and other productive organisms. To understand underlying biological processes and to find out potential new drug targets, we need to understand complete molecular network systems. Systems biology is an approach based on interdisciplinary fields which focuses on systematic study of complex biological systems using new perspective of holism instead of conventional reductionism. Systems biology follows a holistic approach to understand life by using interactomics, genomics, transcriptomics, metabolomics, proteomics, and informational science. In this chapter, we explained different components of systems biology and its connections with other disciplines. In the future, this integrated science can answer several devastating diseases and mysteries in biological systems. They can be readily tested by computer based models.

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Authors and Affiliations

  1. Department of Genetics, Osmania University, Hyderabad, Telangana, 500 007, India

    S. R. Sagurthi, Aravind Setti & Smita C. Pawar

Authors
  1. S. R. Sagurthi
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  2. Aravind Setti
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  3. Smita C. Pawar
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Corresponding author

Correspondence to S. R. Sagurthi .

Editor information

Editors and Affiliations

  1. Sri Biotech Laboratories India Limited, Hyderabad, Telangana, India

    Bir Bahadur

  2. Department of Genetics, University of Delhi, New Delhi, Delhi, India

    Manchikatla Venkat Rajam

  3. Division of Biotechnology, Indian Institute of Horticultural Research (IIHR), Bangalore, Karnataka, India

    Leela Sahijram

  4. Center for Pharmaceutics, Pharmacognosy and Pharmacology, School of Life Sciences, Institute of Trans-Disciplinary Health Science and Technology (IHST), Bangalore, Karnataka, India

    K. V. Krishnamurthy

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Sagurthi, S.R., Setti, A., Pawar, S.C. (2015). Systems Biology: A New Frontier in Science. In: Bahadur, B., Venkat Rajam, M., Sahijram, L., Krishnamurthy, K. (eds) Plant Biology and Biotechnology. Springer, New Delhi. https://doi.org/10.1007/978-81-322-2283-5_14

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