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Agricultural Bioinformatics pp 171–178Cite as

Bioinformatics Strategies Associated with Important Ethnic Medicinal Plants

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Abstract

Plants have been used as a source of medicine since historic times, and herbal drugs play an important role in the treatment of various ailments. Several commercially important modern medicines are of plant-based origin. One of the main purposes to investigate medicinal plants is to understand the main extracts from plants like alkaloids, flavonoids, etc., which can be used as therapeutics for human diseases. Bioinformatics play a crucial role in the analysis and interpretation of high-throughput data generated using molecular biology-based techniques. Bioinformatics approaches leverage plant-based knowledge discovery by offering new tools for the identification of genes and pathways involved in the production of secondary metabolites and also help to identify therapeutically important active compounds. Here we review bioinformatics strategies associated with important ethnic medicinal plants.

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Abbreviations

AP-1:

Activator protein 1

BAX:

BCL2-associated X protein

Bcl-2:

B-cell lymphoma 2

cAMP:

Cyclic adenosine monophosphate

c-Fos:

Cellular oncogene Fos

CREB:

cAMP response element-binding protein

COX2:

Cyclo oxygenase2

CYP3A4:

Cytochrome P450, family 3, subfamily A, polypeptide 4

Egf:

Epidermal growth factor

EST:

Expressed sequence tags

HTML:

HyperText Markup Language

HTTP:

Hypertext Transfer Protocol

IKK:

I kappa B kinase

IUPAC:

International Union of Pure and Applied Chemistry

MCF-7:

Michigan Cancer Foundation-7 (Breast cancer cell line)

MDR:

Multi drug resistance

NF-KB:

Nuclear transcription factor kappa B

NIK:

NF-κB-inducing kinase

ODC:

Ornithine decarboxylase

PhP:

Hypertext preprocessor

RDBMS:

Relational Database Management System

SQL:

Structured Query Language

TNF-α:

Tumour necrosis factor alpha

TPA:

Tissue plasminogen activator

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Authors and Affiliations

  1. Bioinformatics Centre, Kerala Agricultural University, Vellanikkara, Thrissur, Kerala, 680656, India

    Priyanka James, S. Silpa & Raghunath Keshavachandran

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  1. Priyanka James
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  2. S. Silpa
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  3. Raghunath Keshavachandran
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Correspondence to Priyanka James .

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Editors and Affiliations

  1. Department of Genetics, Osmania University, Hyderabad, Andhra Pradesh, India

    Kavi Kishor P.B.

  2. Department of Biotechnology, Birla Institute of Technology, Ranchi, Jharkhand, India

    Rajib Bandopadhyay

  3. Bioclues Organization, IKP Knowledge Park, Picket, Secunderabad, Andhra Pradesh, India

    Prashanth Suravajhala

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James, P., Silpa, S., Keshavachandran, R. (2014). Bioinformatics Strategies Associated with Important Ethnic Medicinal Plants. In: P.B., K., Bandopadhyay, R., Suravajhala, P. (eds) Agricultural Bioinformatics. Springer, New Delhi. https://doi.org/10.1007/978-81-322-1880-7_10

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