Abstract
In today’s world DNA technology is promoted as an alternative approach for advancement over silicon technology. The DNA technology is also used to detect diseases. It needs some molecular computation for which the development of basic circuit unit is required. Basic circuit comprises the AND, OR and NOT gate. In this paper we proposed the design of two-input OR gate with E6 deoxyribozyme whose internal loop is not fixed. OR logic helps to express Boolean expression in Sum of Product (SOP) form and sometimes it uses to minimize the Boolean function. The DNA technology can be used as a substitute method not only for lower time complexity and low power consumption but also this technology is reversible in nature.
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References
Yaakov Benenson, Tamar Paz-Elizur, Rivka Adar, Ehud Keinan, Zvi Livneh and Ehud Shapiro.: Programmable and autonomous computing machine made of biomolecules. Nature. 414, 430–434 (2001).
Yaakov Benenson, Rivka Adar, Tamar Paz-Elizur, Zvi Livneh, and Ehud Shapiro.: DNA molecule provides a computing machine with both data and fuel. Proc. National Acad. Sci. USA. 100 (5), 2191–2196 (2003).
Sakamoto, K., Gouzu, H., Komiya, K., Kiga, D., Yokoyama, S., Yokomori, T. and Hagiya, M.: Molecular computation by DNA hairpin formation Science. 288, 1223–1226 (2000).
Yaakov Benenson, Binyamin Gil, Uri Ben-Dor, Rivka Adar and Ehud Shapiro.: An autonomous molecular computer for logical control of gene expression. Nature. 429, 423–429 (2004).
Yin, P., Choi, H. M. T., Calvert, C. R. and Pierce, N. A.: Programming biomolecular self-assembly pathways. Nature. 451, 318–322 (2008).
Bernard Yurke, Andrew J. Turberfield, Allen P. Mills Jr, Friedrich C. Simmel and Jennifer L. Neumann.: A DNA-fuelled molecular machine made of DNA. Nature. 406, 605–608 (2000).
Venkataraman S., Dirks R. M., Rothemund P. W. K., Winfree E. and Pierce N. A.: An autonomous polymerization motor powered by DNA hybridization. Nature Nano technology. 2, 490–494 (2007).
Seelig, G., Soloveichik, D., Zhang, D. Y. and Winfree E.: Enzyme-free nucleic acid logic circuits. Science. 314, 1585–1588 (2006).
Zhang, D. Y., Turberfield, A. J., Yurke, B. and Winfree E.: Engineering entropy-driven reactions and networks catalyzed by DNA. Science. 318, 1121–1125 (2007).
Kari, L., Paun, G., Rozenberg, G., Salomaa, A. and Yu, S.: DNA computing, sticker systems, and universality, Acta Informatica. 35, 401–420 (1998).
Paun, G. and Rozenberg, G.: Sticker systems. Theoritical Computer Science. 204, 183–203 (1998).
Leonard M. Adleman.: Molecular computation of solutions to combinatorial problem. Science, New Series. 266 (5187), 1021–1024 (1994).
Kunal Das and Debashis De: A study on Diverse Nanostructure for implementing Logic Gate design for QCA. Int. Journal of Nanoscience. 10 (01n02), 1–7 (2011).
Kunal Das and Debashis De: Novel Approach to design A Testable Conservative Logic Gate for QCA Implementation. Proc. IEEE 2nd International Advance Computing Conference. 82–87 (2010).
Kunal Das and Debashis De: A Novel Approach of And-Or-Invert (AOI) Gate design for QCA. Proc. Int. Conference on Computers and Devices for Communication. (2009).
Stojanovic, M. N. and Stefanovic, D.: Deoxyribozyme-Based Half-Adder. Journal of American Chemical Society. 125, 6673–6676 (2003).
Watson, J. D. and Crick, F. H. C.: The Structure of DNA. Cold Spring Harbor Symposia Quantitative Biology. 123–131 (1953).
Breaker, R. R. and Joyce, G. F.: A DNA enzyme with Mg2 + -dependent RNA phosphoesterase activity. Chemistry & Biology. 2, 655–660 (1995).
Jing Li, Wenchao Zheng, Angela H. Kwon, and Yi Lu.: In vitro selection and characterization of a highly efficient Zn(II)-dependent RNA-cleaving deoxyribozyme. Nucleic Acids Res. 28 (2), 481–488 (2000).
Santoro Stephen W. and Joyce, Gerald F.: A general purpose RNA-cleaving DNA enzyme. Proc. National Acad. Sci. USA. 94 (9), 4262–4266 (1997).
Stojanovic M. N., Mitchell T. E. and Stefanovic, D.: Deoxyribozyme-Based Logic Gates. Journal of American Chemical Society. 124, 3555–3561 (2002).
Okamoto A., Tanaka K. and Saito, I.: DNA Logic Gates. Journal of American Chemical Society. 126, 9458–9463 (2004).
Natalia S. Akopyants, Robin S. Matlib, Elena N. Bukanova, Matthew R. Smeds, Bernard H. Brownstein, Gary D. Stormo, Stephen M. Beverley.: Expression profiling using random genomic DNA microarrays identifies differentially expressed genes associated with three major developmental stages of the protozoan parasite Leishmania major. Molecular & Biochemical Parasitology Elsevier. 136, 71–86 (2004).
Tim Head.: Formal Language Theory and DNA: An analysis of the generative capacity of specific recombinant behaviors. Bulletin of Mathematical Biology. 49 (6), 737–759 (1987).
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Roy, P., Dey, D., Sinha, S., De, D. (2013). Reversible OR Logic Gate Design Using DNA. In: Bansal, J., Singh, P., Deep, K., Pant, M., Nagar, A. (eds) Proceedings of Seventh International Conference on Bio-Inspired Computing: Theories and Applications (BIC-TA 2012). Advances in Intelligent Systems and Computing, vol 201. Springer, India. https://doi.org/10.1007/978-81-322-1038-2_30
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DOI: https://doi.org/10.1007/978-81-322-1038-2_30
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