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Evaluation of Hypolipidemic Effect of Various Extracts of Whole Plant of Bauhinia purpurea in Rat Fed with High Fat Diet

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Recent Advancements in System Modelling Applications

Part of the book series: Lecture Notes in Electrical Engineering ((LNEE,volume 188))

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Abstract

The objective of the present study was to investigate the hypolipidemic effect of various extracts of whole plant of Bauhinia purpurea in rat fed with high fat diet. The elevated levels of total cholesterol, ester and free cholesterol, phospholipids, triglycerides, low-density lipoprotein, and very low-density lipoprotein due to high fat diet (HFD). The group receiving ethyl acetate extract of Bauhinia purpurea at the dose of 250 mg/kg (Group IV) was significantly (P < 0.001) reduced the lipid profile and lipoprotein levels. A significant (p < 0.001) reduction in HDL-cholesterol was noticed in HFD fed groups (II); however, a significant increased the HDL level was produced by the administration of ethyl acetate extract of Bauhinia purpurea. There was a noticed increase in the body weight in HFD fed group (II), which was significantly (p < 0.001) reduced by the administration of ethyl acetate extract of Bauhinia purpurea. Therefore, it was concluded that the ethyl acetate extract of whole plant of Bauhinia purpurea as definite cardio protective effect against hyperlipidemia.

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Acknowledgments

The authors are thankful to the Karpagam University, Coimbatore, India, for providing laboratory and technical support for the present investigation.

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Authors and Affiliations

  1. Karpagam University, Coimbatore, India

    C. D. Shajiselvin

  2. Annamalai University, Annamalai Nagar, Chidambaram, India

    A. Kottai Muthu

Authors
  1. C. D. Shajiselvin
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  2. A. Kottai Muthu
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Correspondence to A. Kottai Muthu .

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Editors and Affiliations

  1. , Department of E & I Engineering, Annamalai University, Faculty of Engineering and Technology, Annamalai Nagar, 608002, Tamil Nadu, India

    R Malathi

  2. , Department of E & I Engineering, Annamalai University, Faculty of Engineering and Technology, Annamalai Nagar, 608002, Tamil Nadu, India

    J Krishnan

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Shajiselvin, C.D., Kottai Muthu, A. (2013). Evaluation of Hypolipidemic Effect of Various Extracts of Whole Plant of Bauhinia purpurea in Rat Fed with High Fat Diet. In: Malathi, R., Krishnan, J. (eds) Recent Advancements in System Modelling Applications. Lecture Notes in Electrical Engineering, vol 188. Springer, India. https://doi.org/10.1007/978-81-322-1035-1_36

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  • DOI: https://doi.org/10.1007/978-81-322-1035-1_36

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  • Publisher Name: Springer, India

  • Print ISBN: 978-81-322-1034-4

  • Online ISBN: 978-81-322-1035-1

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