Abstract
Our previous study suggested that the genotyping of latent herpes simplex virus type 1 (HSV-1) in trigeminal ganglion in forensic autopsies were useful for tracing the origins of unidentified cadavers. Here, we tried to isolate HSV-1 from cadaver trigeminal ganglia. Trigeminal ganglia were cultured with Vero cells. DNA was extracted from the culture medium and from the remaining half of each ganglion samples. HSV-1 DNA detection rate of the culture medium was higher than those of the extract taken directly from trigeminal ganglia. These results suggest that latent HSV-1 in trigeminal ganglia may be reactivated.
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Reference
Motani H, Sakurada K, Ikegaya H et al (2006) Detection of herpes simplex virus type 1 DNA in bilateral human trigeminal ganglia and optic nerves by polymerase chain reaction. J Med Virol 78:1584–1587
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Monma, Y., Motani, H., Iwase, H., Fukumoto, S. (2010). Detection of herpes simplex virus type 1 in human cadaver trigeminal ganglia. In: Sasano, T., Suzuki, O. (eds) Interface Oral Health Science 2009. Springer, Tokyo. https://doi.org/10.1007/978-4-431-99644-6_68
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DOI: https://doi.org/10.1007/978-4-431-99644-6_68
Publisher Name: Springer, Tokyo
Print ISBN: 978-4-431-99643-9
Online ISBN: 978-4-431-99644-6
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