Abstract
Transition zone (TZ) cancer is commonly detected in transurethrally resected specimens but also radical prostatectomy specimens. According to a recent study, as many as 14% of stage T1c cancers are exclusively in the TZ. In general, they are small and are of low Gleason score (commonly <6). Because of their anatomic location (away from the “capsule”) and fewer penetrating nerves than in the peripheral zone, they are less likely to behave aggressively than those arising in non-TZs. As the volume increases, however, they may become more aggressive and can invade the anterior fibromuscular stroma, seminal vesicles, and pelvic lymph nodes. Microscopically, most transition zone carcinomas consist of well-differentiated glands of widely variable size and contour lined by tall columnar cells with clear cytoplasm.
Keywords
- Benign Prostate Hyperplasia
- Seminal Vesicle
- Gleason Score
- Pelvic Lymph Node
- Radical Prostatectomy Specimen
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
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(2008). What are the characteristics of transition zone cancer? Is it less aggressive than the non-transition-zone cancer?. In: Questions in Daily Urologic Practice. Springer, Tokyo. https://doi.org/10.1007/978-4-431-72819-1_6
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DOI: https://doi.org/10.1007/978-4-431-72819-1_6
Publisher Name: Springer, Tokyo
Print ISBN: 978-4-431-72818-4
Online ISBN: 978-4-431-72819-1
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