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Reperfusion in Patients with the “Spectacular Shrinking Deficit” Demonstrated by 99mTc-hexamethylpropyleneamine Oxime Single Photon Emission Computed Tomography

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Thrombolytic Therapy in Acute Ischemic Stroke III

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Abstract

The “spectacular shrinking deficit” (SSD) [1–4] refers to a syndrome of profound hemispheric ischemia that resolves rapidly over hours to days leaving patients with minimal residual neurological deficits. It is postulated that the SSD results from rapid clot lysis, fragmentation, and migration along the internal carotid-middle cerebral arterial axis, with tissue perfusion being restored before irreversible damage has occurred. Clot migration has been demonstrated angiographically in this syndrome [4]; however, the tissue perfusion changes have not previously been described.

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References

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Author information

Authors and Affiliations

  1. Department of Neurology, Austin Hospital, Burgundy Street, Heidelberg, Melbourne, Victoria, 3084, Australia

    A. E. Baird & G. A. Donnan

  2. Department of Nuclear Medicine, Austin Hospital, Burgundy Street, Heidelberg, Melbourne, Victoria, 3084, Australia

    M. C. Austin & W. J. McKay

  3. Department of Medicine, University of Melbourne, Victoria, Australia

    A. E. Baird & G. A. Donnan

Authors
  1. A. E. Baird
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  2. G. A. Donnan
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  3. M. C. Austin
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  4. W. J. McKay
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Editor information

Editors and Affiliations

  1. Cerebrovascular Division, Department of Internal Medicine, National Cardiovascular Center, 5-7-1 Fujishirodai, Suita, Osaka, 565, Japan

    Takenori Yamaguchi M.D., D.M.Sc.  & Kazuo Minematsu M.D., D.M.Sc.  & 

  2. Clinical Neurosciences, Hyogo Institute for Aging Brain and Cognitive Disorders, 520 Saisho-ku, Himeji, Hyogo, 670, Japan

    Etsuro Mori M.D.

  3. Department of Molecular and Experimental Medicine, The Scripps Research Institute and Division of Hematology/Medical Oncology, Scripps Clinic and Research Foundation, 10666 North Torrey Pines Road, 92037, La Jolla, CA, USA

    Gregory J. del Zoppo M.D.

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© 1995 Springer-Verlag Tokyo

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Baird, A.E., Donnan, G.A., Austin, M.C., McKay, W.J. (1995). Reperfusion in Patients with the “Spectacular Shrinking Deficit” Demonstrated by 99mTc-hexamethylpropyleneamine Oxime Single Photon Emission Computed Tomography. In: Yamaguchi, T., Mori, E., Minematsu, K., del Zoppo, G.J. (eds) Thrombolytic Therapy in Acute Ischemic Stroke III. Springer, Tokyo. https://doi.org/10.1007/978-4-431-68459-6_38

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  • DOI: https://doi.org/10.1007/978-4-431-68459-6_38

  • Publisher Name: Springer, Tokyo

  • Print ISBN: 978-4-431-70139-2

  • Online ISBN: 978-4-431-68459-6

  • eBook Packages: Springer Book Archive

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