Abstract
A new model to explain a possible mechanism for atherogenesis is presented. The model is based upon the fact that when the flow is separated there is a increase in pressure in the separated region. Further, if the separation is three-dimensional, there are spiral vortices, with axes parallel to the axis of the artery. Both these factors cause an increase in the arterial wall tension near the separated regions. The increase in the azimuthal wall tension results in axially oriented lesions. Numerical methods are used to compute the flow in systems of channels and in a three-dimensional flow past an atheroma. Such theoretical flow computations can be useful in quantifying different factors in atherogenesis.
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References
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© 1988 Springer-Verlag Tokyo
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Fuchs, L., Erikson, U., Smedby, O. (1988). The Role of Flow Separation and Its Prediction in Arterial Flows. In: Yoshida, Y., Yamaguchi, T., Caro, C.G., Glagov, S., Nerem, R.M. (eds) Role of Blood Flow in Atherogenesis. Springer, Tokyo. https://doi.org/10.1007/978-4-431-68399-5_18
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DOI: https://doi.org/10.1007/978-4-431-68399-5_18
Publisher Name: Springer, Tokyo
Print ISBN: 978-4-431-68401-5
Online ISBN: 978-4-431-68399-5
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