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Remnant Stomach and Gastric Cancer

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Gastric Cancer

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Abstract

Before the modern era of H2-receptor antagonists and proton pump inhibitors, gastric surgery was the sole effective treatment for ulcer disease. Successful partial gastrectomy with gastroduodenostomy was first performed by Theodor Billroth in 1881 for distal gastric carcinoma; 1 year later Ludwik Rydygier performed a similar operation for ulcer disease with gastric outlet obstruction. Over the next few decades the Billroth I- operation was extensively attempted and modified. In 1885 Billroth introduced another anastomotic principle, using closure of the duodenum and a gastrojejunostomy (Billroth II). Parallel with the introduction of partial gastrectomy, Wölfler designed a gastrojejunostomy which was favored by most surgeons, being an easier, more rapid, and thus safer method. However, due to the high frequency of postoperative complications this method was abandoned in the 1920s and partial gastrectomy according to Billroth I or Billroth II became the method of choice. The latter operation took over as the standard procedure in peptic ulcer disease, reaching its peak of popularity in the mid 1950s. Later Billroth I regained popularity but was soon taken over by proximal gastric vagotomy.

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References

  1. Bloom B, Fendrick M, Ramsey S (1990) Changes in peptic ulcer and gastritis/ duodenitis in Great Britain 1970–1985. J Clin Gastroenterol 12: 100–108

    Article  PubMed  CAS  Google Scholar 

  2. Fineberg H, Pearlman L (1981) Surgical treatment of peptic ulcer in the United States. Trends before and after the introduction of cimetidine. Lancet I: 1305–1307

    Google Scholar 

  3. Balfour DC (1922) Factors influencing the life expectancy of patients operated on for gastric ulcer. Ann Surg 76: 405–408

    Article  PubMed  CAS  Google Scholar 

  4. Freedman M, Berne C (1954) Gastric carcinoma of the gastrojejunal stoma. Gastroenterology 27: 210–215

    PubMed  CAS  Google Scholar 

  5. Helsingen N, Hillestad L (1956) Cancer development in the gastric stump after partial gastrectomy for ulcer. Ann Surg 143: 173–179

    PubMed  CAS  Google Scholar 

  6. Peitsch W (1979) Remarks on frequency and pathogenesis of primary gastric stump cancer. In: Herfarth C, Schlag P (eds) Gastric cancer. Springer, New York, pp 137–144

    Chapter  Google Scholar 

  7. Tersmette AC, Giardiello FM, Offerhaus GJA, Tersmette KWF, Ohara K, Vandenbroucke JP, Tytgat GNJ (1991) Geographical variance in the risk of gastric stump cancer: No increased risk in Japan? Jpn J Cancer Res 82: 266–272

    Article  PubMed  CAS  Google Scholar 

  8. Dockray GJ (1992) Gastric peptides. In: Gustaysson S, Kumar D, Graham D (eds) The stomach. Churchill Livingstone, London, pp 103–127

    Google Scholar 

  9. Fischer AB, Graem N, Christiansen L (1983) Causes and clinical significance of gastritis following Billroth II resection for duodenal ulcer. Br J Surg 70: 322–325

    Article  PubMed  CAS  Google Scholar 

  10. Stael von Holstein C (1992) Gastric stump carcinoma. A clinical study on carcinoma in the gastric remnant after surgery for benign gastroduodenal disease. Thesis, bulletin no 84, Department of Surgery, University of Lund

    Google Scholar 

  11. Tatsuta M, Yamamura, Taniguchi H, Tamura H (1982) Gastrin protection against chemically induced gastric adenocarcinomas in Wistar rats: Histopathology of the glandular stomach and incidence of gastric adenocarcinoma. J Natl Cancer Inst 69: 59–66

    Google Scholar 

  12. Lawson HH (1979) Duodenogastric reflux and epithelial lesions. In: Herfarth C, Schlag P (eds) Gastric cancer. Springer New York, pp 112–119

    Google Scholar 

  13. Domellöf L, Janunger KG (1978) Polyps in the gastric remnant after partial gastrectomy. Acta Chir Scand 144: 293–298

    PubMed  Google Scholar 

  14. Domellöf L (1979) Gastric carcinoma promoted by alkaline reflux gastritis—with special reference to bile and other surfactants as promoters of postoperative gastric cancer. Med Hypotheses 5: 463–476

    Article  PubMed  Google Scholar 

  15. Domellöf L, Reddy BS, Weisburger JH (1980) Microflora and deconjugation of bile acids in alkaline reflux after partial gastrectomy. Am J Surg 140: 291–295

    Article  PubMed  Google Scholar 

  16. Salomoni M, Zuccato E, Granelli P, Montorsi W, Doldi SB, Germiniani R, Mussini E (1989) Effect of bile salts on carbonic anhydrase from rat and human gastric mucosa. Scand J Gastroenterol 24: 28–32

    Article  PubMed  CAS  Google Scholar 

  17. Dewar P, King R, Johnston D (1982) Bile acid and lysolecithin concentrations in the stomach in patients with duodenal ulcer before operation and after treatment by highly selective vagotomy, partial gastrectomy, or truncal vagotomy and drainage. Gut 23: 569–577

    Article  PubMed  CAS  Google Scholar 

  18. Dahm. K, Werner B, Eichen R, et al (1979) Experimental cancer of the gastric stump. In: Herfarth C, Schlag P (eds) Gastric cancer. Springer, New York, pp 44–69

    Chapter  Google Scholar 

  19. Langhans P, Heger R, Hohenstein J, Bunte H (1981) Gastric stump carcinoma—new aspects deduced from experimental results. Scand J Gastroenterol 67 [Suppl]: 161–164

    CAS  Google Scholar 

  20. Kawahara A, Saito T, Kobayashi M (1989) Bile acids promote carcinogenesis in the remnant stomach of rats. J Cancer Res Clin Oncol 115: 423–428

    Article  Google Scholar 

  21. Mason R, Filipe I (1990) The aetiology of gastric stump carcinoma in the rat. Scand J Gastroenterol 25: 961–965

    Article  PubMed  CAS  Google Scholar 

  22. Mortensen NJMcC, Houghton PWJ (1988) Bile and enterogastric reflux—a factor in gastric cancer? In: Reeds PI, Hill MJ (eds) Gastric carcinogenesis, Excerpta Medica IV series. Excerpta Medica, Amsterdam

    Google Scholar 

  23. Domellöf L, Eriksson S, Janunger KG (1977) Carcinoma and possible precancerous changes of the gastric stump after Billroth II resection. Gastroenterology 73: 462468

    Google Scholar 

  24. Correa P, Haenszel W, Cuello C, Tannenbaum S, Archer M (1975) A model for gastric cancer epidemiology. Lancet II: 58–59

    Google Scholar 

  25. Hill MJ (1988) Gastric carcinogenesis: Luminal factors. In: Reeds PI, Hill MJ (eds) Gastric carcinogenesis, Excerpta Medica IV series. Excerpta Medica, Amsterdam

    Google Scholar 

  26. Lundegârdh G (1991) Mortality and cancer incidence following partial gastrectomy for benign ulcer disease. Thesis, Uppsala University

    Google Scholar 

  27. Muscroft T, Deane S, Youngs D, Burdon D, Keighley M (1981) The microflora of the postoperative stomach. Br J Surg 68: 560–564

    Article  PubMed  CAS  Google Scholar 

  28. Marshall BJ, Warren JR (1984) Unidentified curved bacilli in the stomach of patients with gastritis and peptic ulceration. Lancet II: 1311–1314

    Google Scholar 

  29. Talley NJ, Zinsmeister AR, Weaver A, DiMagno EP, Carpenter HA, Perez-Perez GI, Blaser MJ (1991) Gastric adenocarcinoma and Helicobacter pylori infection. J Natl Cancer Inst 83: 1734–1739

    Article  PubMed  CAS  Google Scholar 

  30. Offerhaus GJA, van der Stadt J, Huibregtse K, Tersmette AC, Tytgat GNJ (1989) The mucosa of the gastric remnant harboring malignancy. Cancer 64: 698–703

    Article  PubMed  CAS  Google Scholar 

  31. Sipponen P (1989) Atrophic gastritis as a premalignant condition. Ann Med 21: 287–290

    Article  PubMed  CAS  Google Scholar 

  32. Konjetzny GE (1928) Die Entzündung des Magens. In: Henke F, Lubarsch O (eds) Handbuch der speziellen pathologischen Anatomie und Histologie, vol 4/2. Springer, Berlin, pp 768–1175

    Google Scholar 

  33. Konjetzny GE (1938) Der Magenkrebs. Enke, Stuttgart

    Google Scholar 

  34. Konjetzny GE (1943) Die Beziehungen zwischen Gastritis und Magenkrebsentwicklung. Langenbecks Arch Klin Chir 204: 4–63

    Google Scholar 

  35. Janunger KG, Domellöf L, Eriksson S (1978) The development of mucosal changes after gastric surgery for ulcer disease. Scand J Gastroenterol 13: 217–223

    Article  PubMed  CAS  Google Scholar 

  36. Siurala M, Lehtola J, Ihamaki T (1968) Atrophic gastritis and its sequelae. Scand J Gastroenterol 3: 211–223

    Article  PubMed  CAS  Google Scholar 

  37. Eriksson SBS (1983) The operated stomach—A clinical study on late morbidity and mortality rates in patients operated on for benign gastroduodenal diesease, with special reference to the risk of developing gastric cancer. Thesis; bulletin no 36, Department of Surgery, University of Lund

    Google Scholar 

  38. Fujita S (1976) Kinetics of cellular proliferation and growth of human cancers. In: Sugimura T, Yamamura Y (eds) Cancer. Iwanami, Tokyo

    Google Scholar 

  39. Filipe MI (1988) Intestinal metaplasia in the histogenesis of gastric carcinoma. In: Reeds PI, Hill MJ (eds) Gastric carcinogenesis, Excerpta Medica IV series. Excerpta Medica, Amsterdam

    Google Scholar 

  40. Savalgi RS, Corbishley CM, Caygill C, Hill M, Cook MG, Kirkham JS, Northfield TC (1990) Relation between severity and extent of precancerous lesions in the postoperative stomach. Lancet II: 413–416

    Google Scholar 

  41. Morson BC, Sobin LH, Grundmann E, Johansen A, Nagayo T, Serck-Hanssen A (1980) Precancerous conditions and epithelial dysplasia in the stomach. J Clin Pathol 33: 711–721

    Article  PubMed  CAS  Google Scholar 

  42. Graem N, Fischer AB, Beck H (1984) Dysplasia and carcinoma in the Billroth II resected stomach. Acta Pathol Microbiol Immunol Scand [A] 92: 185–188

    CAS  Google Scholar 

  43. Domellöf L, Eriksson S, Helander HF, Janunger KG (1977) Lipid islands in the gastric mucosa after resection for benign ulcer disease. Gastroenterology 72: 1418

    Google Scholar 

  44. Laxen F, Sipponen P, Ihamäki T, Hakkilouto A, Dortcheva Z (1982) Gastric polyps; their morphological and endoscopical characteristics and relation to carcinoma. Acta Pathol Microbiol Immunol Scand [A] 90: 221–228

    CAS  Google Scholar 

  45. Norfleet R, Johnson S (1989) Strange bedfellows: Duodenal ulcer and cancer of the stomach. J Clin Gastroenterol 11: 382–385

    Google Scholar 

  46. Domellöf L (1986) Risk of carcinoma after partial gastrectomy. In: Inokuchi K (ed) Gann monograph on cancer research 31: 205–211

    Google Scholar 

  47. Tersmette AC, Goodman SN, • Offerhaus GJA, Tersmette KWF, Giardiello FM, Vandenbroucke JP, Tytgat GNJ (1991) Multivariate analysis of the risk of stomach cancer after ulcer surgery in an Amsterdam cohort of postgastrectomy patients. Am J Epidemiol 134: 14–21

    CAS  Google Scholar 

  48. Stalsberg H, Taksdal S (1971) Stomach cancer following gastric surgery for benign conditions. Lancet II: 1175–1179

    Google Scholar 

  49. Stael von Holstein C, Eriksson S, Huldt B, Hammar E (1991) Endoscopic screening during 17 years for gastric stump carcinoma. A prospective clinical trial. Scand J Gastroenterol 26: 1020–1026

    Google Scholar 

  50. Dilin C, Sarfati E, Chevrel JP (1985) Les cancers dits "du moignon gastrique". J Chir (Paris) 122: 193–200

    CAS  Google Scholar 

  51. Sasako M, Maruyama K, Kinoshita T, Okabayashi K (1991) Surgical treatment of carcinoma of the gastric stump. Br J Surg 78: 822–824

    Article  PubMed  CAS  Google Scholar 

  52. Krause U (1958) Late prognosis after partial gastrectomy for ulcer. Acta Chir Scand 114:341— 354

    Google Scholar 

  53. Liavaag K (1962) Cancer development in the gastric stump after partial gastrectomy. Ann Surg 155: 103–106

    Article  PubMed  CAS  Google Scholar 

  54. McLean Ross AH, Smith MA, Anderson JR, Small WP (1982) Late mortality after surgery for peptic ulcer. N Engl J Med 307: 519–522

    Article  Google Scholar 

  55. Tokudome S, Kono S, Ikeda M, Karatsune M, Sano C, Inokuchi K, Kodama Y, Ischimiya H, Kanayama F, Faibara N, Koga S, Yamada H, Ikejiri T, Oka N, Tsurumaru H (1984) A prospective study on primary gastric stump cancer following partial gastrectomy for benign gastroduodenal diseases. Cancer Res 44: 2208–2212

    PubMed  CAS  Google Scholar 

  56. Caygill C, Hill M, Kirkham J, Northfield T (1986) Mortality from gastric cancer following surgery for peptic ulcer. Lancet I: 929–931

    Google Scholar 

  57. Viste A, Björnestad E, Opholm P, Skarstein A, Thunold J, Hartveit F, Eide GE, Eide TJ, Söreide 0 (1986) Risk of carcinoma following gastric operations for benign disease: A historical cohort study of 3470 patients. Lancet 11: 502–505

    Google Scholar 

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Author information

Authors and Affiliations

  1. Department of Surgery, Örebro Medical Center Hospital, S-70185, Örebro, Sweden

    Lennart Domellöf

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  1. Lennart Domellöf
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Editor information

Editors and Affiliations

  1. Cancer Institute Hospital, 1-37-1 Kami-Ikebukuro, Toshima-ku, Tokyo, 170, Japan

    Mitsumasa Nishi M.D.

  2. National Cancer Center Hospital, 5-1-1 Tsukiji, Chuo-ku, Tokyo, 104, Japan

    Heizaburo Ichikawa M.D.

  3. Department of Surgery, Cancer Institute Hospital, 1-37-1 Kami-Ikebukuro, Toshima-ku, Tokyo, 170, Japan

    Toshifusa Nakajima M.D.

  4. Gastric Surgery Division, National Cancer Center Hospital, 5-1-1 Tsukiji, Chuo-ku, Tokyo, 104, Japan

    Keiichi Maruyama M.D.

  5. Department of Pathology, Hiroshima University School of Medicine, 1-2-3 Kasumi, Minami-ku, Hiroshima, 734, Japan

    Eiichi Tahara M.D.

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© 1993 Springer Japan

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Domellöf, L. (1993). Remnant Stomach and Gastric Cancer. In: Nishi, M., Ichikawa, H., Nakajima, T., Maruyama, K., Tahara, E. (eds) Gastric Cancer. Springer, Tokyo. https://doi.org/10.1007/978-4-431-68328-5_12

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  • DOI: https://doi.org/10.1007/978-4-431-68328-5_12

  • Publisher Name: Springer, Tokyo

  • Print ISBN: 978-4-431-68330-8

  • Online ISBN: 978-4-431-68328-5

  • eBook Packages: Springer Book Archive

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