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Current Aspects of Blood Coagulation, Fibrinolysis, and Platelets pp 135–139Cite as

The Role of Platelet PAI-1 in the Platelet Rich Plasma Clot Lysis

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Abstract

Plasminogen activator inhibitor-1 (PAI-1) is physiologically the most important inhibitor of tissue plasminogen activator(t-PA) in plasma(1). It has been suggested that more than 80 to 90% of PAI-1 is stored in the platelet α-granules(2,3). It is not clear, however, whether PAI-1 released from platelet plays an important role in the clot lysis.

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Author information

Authors and Affiliations

  1. Dept. of Physiology, Hamamatsu University School of Medicine, Hamamatsu, Shizuoka, Japan

    K. Serizawa, T. Urano, K. Sakakibara, Y. Takada & A. Takada

  2. Dept. of Medicine, Hamamatsu University School of Medicine, Hamamatsu, Shizuoka, Japan

    Y. Kozima

Authors
  1. K. Serizawa
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  2. T. Urano
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  3. Y. Kozima
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  4. K. Sakakibara
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  5. Y. Takada
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  6. A. Takada
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Editor information

Editors and Affiliations

  1. Department of Laboratory Medicine, National Taiwan University Hospital, Taipei, Taiwan

    Ming-Ching Shen (Professor and Chairman) (Professor and Chairman)

  2. Department of Pharmacology, College of Medicine, National Taiwan University, Taipei, Taiwan

    Che-Ming Teng (Professor and Chairman) (Professor and Chairman)

  3. Department of Physiology, School of Medicine, Hamamatsu University, 431-31, Hamamatsu, Shizuoka, Japan

    Akikazu Takada (Professor and Chairman) (Professor and Chairman)

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© 1993 Springer Japan

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Serizawa, K., Urano, T., Kozima, Y., Sakakibara, K., Takada, Y., Takada, A. (1993). The Role of Platelet PAI-1 in the Platelet Rich Plasma Clot Lysis. In: Shen, MC., Teng, CM., Takada, A. (eds) Current Aspects of Blood Coagulation, Fibrinolysis, and Platelets. Springer, Tokyo. https://doi.org/10.1007/978-4-431-68323-0_23

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  • DOI: https://doi.org/10.1007/978-4-431-68323-0_23

  • Publisher Name: Springer, Tokyo

  • Print ISBN: 978-4-431-70123-1

  • Online ISBN: 978-4-431-68323-0

  • eBook Packages: Springer Book Archive

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