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Hemostatic and Fibrinolytic Changes in Herpes Zoster

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Current Aspects of Blood Coagulation, Fibrinolysis, and Platelets

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Abstract

When the patients with herpes zoster (HZ) have severe underlying diseases or being treated with immunosuppressive agents, they may occasionally develop severe complications such as disseminated intravascular coagulation (DIC) or encephalitis [1,2]. Histopathological examination of herpetic lesion revealed that endothelial cells are damaged, suggesting that some mechanism takes place to induce hypercoagulable condition in this disease [2,3]. However, effects of varicella zoster virus (VZV) infection to coagulation and fibrinolysis system have not been fully documented. This study investigates changes of platelet count and hemostatic and fibrinolytic molecular markers. Influencing factors to hemostatic and fibrinolytic conditions such as location and size of lesions, dissemination, and pleocytosis of cerebrospinal fluid were analyzed. The age of the patient was found to be crucial factor to modify hemostatic and fibrinolytic changes in HZ.

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Author information

Authors and Affiliations

  1. Department of Dermatology, Saitama Medical Center, Saitama Medical School, 1981 Kamoda, Tsujido, Kawagoe 350, Japan

    Y. Yoshizawa, Y. Shinozaki, S. Izaki & K. Kitamura

Authors
  1. Y. Yoshizawa
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  2. Y. Shinozaki
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  3. S. Izaki
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  4. K. Kitamura
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Editor information

Editors and Affiliations

  1. Department of Laboratory Medicine, National Taiwan University Hospital, Taipei, Taiwan

    Ming-Ching Shen (Professor and Chairman) (Professor and Chairman)

  2. Department of Pharmacology, College of Medicine, National Taiwan University, Taipei, Taiwan

    Che-Ming Teng (Professor and Chairman) (Professor and Chairman)

  3. Department of Physiology, School of Medicine, Hamamatsu University, 431-31, Hamamatsu, Shizuoka, Japan

    Akikazu Takada (Professor and Chairman) (Professor and Chairman)

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© 1993 Springer Japan

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Yoshizawa, Y., Shinozaki, Y., Izaki, S., Kitamura, K. (1993). Hemostatic and Fibrinolytic Changes in Herpes Zoster. In: Shen, MC., Teng, CM., Takada, A. (eds) Current Aspects of Blood Coagulation, Fibrinolysis, and Platelets. Springer, Tokyo. https://doi.org/10.1007/978-4-431-68323-0_15

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  • DOI: https://doi.org/10.1007/978-4-431-68323-0_15

  • Publisher Name: Springer, Tokyo

  • Print ISBN: 978-4-431-70123-1

  • Online ISBN: 978-4-431-68323-0

  • eBook Packages: Springer Book Archive

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