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Effects of Anticoagulants on Thrombolysis Mediated by Tissue Plasminogen Activator in Experimental Thrombosis Model

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Current Aspects of Blood Coagulation, Fibrinolysis, and Platelets

Abstract

Tissue plasminogen activator (t-PA) is being used as thrombolytic therapy for patients with acute myocardial infarction [1], given in combination with anticoagulants such as heparin or warfarin. We compared the effects of the new selective thrombin inhibitors, argatroban and hirudin, with those of heparin, on the thrombolysis mediated by t-PA in an experimental model of thrombosis using the hamster cheek pouch.

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© 1993 Springer Japan

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Nakagawa, K. et al. (1993). Effects of Anticoagulants on Thrombolysis Mediated by Tissue Plasminogen Activator in Experimental Thrombosis Model. In: Shen, MC., Teng, CM., Takada, A. (eds) Current Aspects of Blood Coagulation, Fibrinolysis, and Platelets. Springer, Tokyo. https://doi.org/10.1007/978-4-431-68323-0_13

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  • DOI: https://doi.org/10.1007/978-4-431-68323-0_13

  • Publisher Name: Springer, Tokyo

  • Print ISBN: 978-4-431-70123-1

  • Online ISBN: 978-4-431-68323-0

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