Adenocarcinoma Arising in Barrett’s Esophagus After Esophageal Resection and Jejunal Interposition

  • Örs Péter Horváth
  • Jolán Csanádi
  • Vilmos Szendrényi
Conference paper


There are a lot of open questions about the pathogenesis of Barrett’s esophagus. Some of them are listed below:
  1. 1.

    Is the presence of gastroesophageal reflux necessary to elicit development of a columnar-lined esophagus?

  2. 2.

    Is Barrett’s esophagus merely due to an excessive alkaline exposure or are there some specific factors, such as certain components of bile or pancreatic enzymes, also necessary for the formation of a columnarlined esophagus?

  3. 3.

    Where does the metaplastic epithelium arise from? (The new adenomatosus lining develops either from submucosal glands of the esophageeal mucosa or from adjacent tissues.)

  4. 4.

    Does columnar epithelium regress after a successful antireflux repair?



Antireflux Surgery Columnar Epithelium Esophageal Resection Submucosal Gland Jejunal Interposition 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer-Verlag Tokyo 1993

Authors and Affiliations

  • Örs Péter Horváth
    • 1
  • Jolán Csanádi
    • 2
  • Vilmos Szendrényi
    • 2
  1. 1.Department of SurgeryMedical University of PécsPécsHungary
  2. 2.Department of Surgery and PathologyAlbert Szent-Györgyi Medical University of SzegedSzegedHungary

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