Abstract
The effect of Ryanodine and CoQ10 on intracellular electrolyte alter¬ations of rabbit heart was investigated. Electrolyte concentrations in the contractile element (A band) of the myocardial cells (ventricular cells) were measured by X-ray microanalysis employing thin sections of freshly freeze-dried myocardium.
These data suggest that intracellular Ca accumulation may occur during reperfusion and the accumulation may be prevented by the administration of Ryanodine and CoQ10
The possible mechanism of the effects of Ryanodine and CoQ10 on the electrolyte alterations of myocardium are discussed.
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© 1992 Springer-Verlag Tokyo
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Morita, M. et al. (1992). Myocardial Protection with Ryanodine and CoQ10 Against Post-ischemic Reperfusion Injury of Rabbit Heart. In: Yasuda, H., Kawaguchi, H. (eds) New Aspects in the Treatment of Failing Heart. Springer, Tokyo. https://doi.org/10.1007/978-4-431-68219-6_40
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DOI: https://doi.org/10.1007/978-4-431-68219-6_40
Publisher Name: Springer, Tokyo
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Online ISBN: 978-4-431-68219-6
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