Abstract
For about 20 years the diastolic part of the cardiac cycle was increasingly taken into consideration [1, 9, 2] especially with respect to ischemic heart disease [6, 7]. Particularly the load-dependence of relaxation — the analogue of the FRANK-STARLING LV function curves — occupied high interest. Using the four tools ouabain, caffeine, gallopamil and Mg++ the following studies should con¬tribute to elucidate the interaction between myocardial intra-/extracellular Ca status and load depend¬ence of -dp/dtmax (as a measure of diastolic relaxation).
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© 1992 Springer-Verlag Tokyo
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Döring, J., Hiller, V., Bunsiricomchai, P. (1992). Load Dependence of Systolic and Diastolic LV Function — On-line Recorded in the Isolated Perfused Guinea Pig Heart. Effects of Ouabain, Caffeine, Gallopamil and [Mg++]O . In: Yasuda, H., Kawaguchi, H. (eds) New Aspects in the Treatment of Failing Heart. Springer, Tokyo. https://doi.org/10.1007/978-4-431-68219-6_33
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DOI: https://doi.org/10.1007/978-4-431-68219-6_33
Publisher Name: Springer, Tokyo
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