Abstract
Postoperative analgesia is often provided with a continuous intravenous infusion of morphine with the infusion rate altered by the nursing staff as required. However, the time to the peak effect of an intravenous bolus dose of morphine is about 15–20 minutes. A change in the infusion rate of morphine will therefore not achieve its full effect for a considerable period of time, Alfentanil has the main benefit over morphine of rapid onset of action but it also has the disadvantage that it is also rapidly eliminated and re-distributed. Administration by patient controlled analgesia (PCA) has not proved satisfactory [1, 2] and some type of continuous alfentanil infusion is necessary to provide postoperative analgesia.
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© 1992 Springer-Verlag Tokyo
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Kenny, G.N., Davies, F.W., White, M. (1992). Computerised Alfentanil Infusion in Postoperative Analgesia. In: Ikeda, K., Doi, M., Kazama, T., Sato, K., Oyama, T. (eds) Computing and Monitoring in Anesthesia and Intensive Care. Springer, Tokyo. https://doi.org/10.1007/978-4-431-68201-1_34
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DOI: https://doi.org/10.1007/978-4-431-68201-1_34
Publisher Name: Springer, Tokyo
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